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Product Info Summary
| SKU: | A09748 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | IP, IHC, WB |
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Product info
Product Name
Anti-Twinfilin-2 TWF2 Antibody
SKU/Catalog Number
A09748
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Twinfilin-2 TWF2 Antibody catalog # A09748. Tested in WB,IHC,IP applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Twinfilin-2 TWF2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09748)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human RFWD3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09748 is reactive to TWF2 in Human, Mouse
Applications
A09748 is guaranteed for IP, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
39.548kDa
Background of TWF2
E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Ota T., Nat. Genet. 36:40-45(2004).
Matsuoka S., Science 316:1160-1166(2007).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
IP: 1:20-1:50
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For TWF2 (Source: Uniprot.org, NCBI)
Gene Name
TWF2
Full Name
Twinfilin-2
Weight
39.548kDa
Superfamily
actin-binding proteins ADF family
Alternative Names
A6-related protein; A6RPFLJ56277; hA6RP; protein tyrosine kinase 9-like (A6-related protein); Protein tyrosine kinase 9-like; PTK9L protein tyrosine kinase 9-like (A6-related protein); PTK9LA6r; twinfilin, actin-binding protein, homolog 2 (Drosophila); Twinfilin-1-like protein; twinfilin-2 TWF2 A6RP, A6r, MSTP011, PTK9L twinfilin actin binding protein 2 twinfilin-2|A6-related protein|PTK9L protein tyrosine kinase 9-like (A6-related protein)|protein tyrosine kinase 9-like (A6-related protein)|twinfilin, actin-binding protein, homolog 2|twinfilin-1-like protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TWF2, check out the TWF2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TWF2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Twinfilin-2 TWF2 Antibody (A09748)
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No publications found for A09748
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