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Product Info Summary
| SKU: | M01219-2 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | WB |
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Product info
Product Name
Anti-TXN Antibody
View all Thioredoxin-1 Antibodies
SKU/Catalog Number
M01219-2
Size
50 µl
Description
Boster Bio Anti-TXN Antibody (Catalog # M01219-2). Tested in WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-TXN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01219-2)
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
1850CT339.14.1
Isotype
IgG1,k
Immunogen
This antibody is generated from a mouse immunized with a recombinant protein from human.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01219-2 is reactive to TXN in Human
Reconstitution
Calculated molecular weight
11737 Da
Background of Thioredoxin-1
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M01219-2 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000
Validation Images & Assay Conditions
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All lanes : Anti-TXN at 1:2000 dilution
Lane 1: SH-SY5Y whole cell lysate
Lane 2: A431 whole cell lysate
Lane 3: Hela whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 12 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For TXN (Source: Uniprot.org, NCBI)
Gene Name
TXN
Full Name
Thioredoxin
Weight
11737 Da
Superfamily
thioredoxin family
Alternative Names
Thioredoxin, Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP, TXN, TRDX, TRX, TRX1 TXN TRDX, TRX, TRX1, Trx80 thioredoxin thioredoxin|ADF|ATL-derived factor|SASP|TXN delta 3|surface-associated sulphydryl protein|testicular tissue protein Li 199|thioredoxin delta 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TXN, check out the TXN Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TXN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TXN Antibody (M01219-2)
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