Anti-TYK2 Antibody

TYK2 antibody

Boster Bio Anti-TYK2 Antibody (Catalog # A01642-1). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01642-1
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, WB

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Product Name

Anti-TYK2 Antibody

View all TYK2 Antibodies

SKU/Catalog Number

A01642-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TYK2 Antibody (Catalog # A01642-1). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

TYK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-TYK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01642-1)

Host

Rabbit

Contents

TYK2 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

Rabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2. The immunogen is located within amino acids 90 - 140 of TYK2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

At least three isoforms of TYK2 are known to exist; this antibody only detects the two longest isoforms.

Reactive Species

A01642-1 is reactive to TYK2 in Human, Mouse, Rat

Applications

A01642-1 is guaranteed for ELISA, IF, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

133.65kDa

Background of TYK2

TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TYK2 antibody can be used for detection of TYK2 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For TYK2 (Source: Uniprot.org, NCBI)

Gene Name

TYK2

Full Name

Non-receptor tyrosine-protein kinase TYK2

Weight

133.65kDa

Superfamily

protein kinase superfamily

Alternative Names

EC 2.7.10; EC 2.7.10.2; JTK1; non-receptor tyrosine-protein kinase TYK2; Tyk2; tyrosine kinase 2 TYK2 IMD35, JTK1 tyrosine kinase 2 non-receptor tyrosine-protein kinase TYK2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TYK2, check out the TYK2 Infographic

TYK2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TYK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01642-1-0.1 mg

0.1 mg

$449

Free Secondary Antibody

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A01642-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$449.00

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