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Product Info Summary
| SKU: | A01539 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC |
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Product info
Product Name
Anti-Tyrosine-protein kinase Blk Blk Antibody
SKU/Catalog Number
A01539
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Tyrosine-protein kinase Blk Blk Antibody catalog # A01539. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Tyrosine-protein kinase Blk Blk Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01539)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Blk around the non-phosphorylation site of Y501.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01539 is reactive to BLK in Human, Mouse, Rat
Applications
A01539 is guaranteed for ELISA, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
57.706kDa
Background of BLK
Isoform 1:Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.Isoform 3:Promotes cell to cell and cell to substratum adhesion, increases the cell proliferation rate and leads to cytokeratin hyper-expression (when overexpressed in HeLa cells).
Heiss N.S., Nat. Genet. 19:32-38(1998).
Knight S.W., Am. J. Hum. Genet. 65:50-58(1999).
Hassock S., Genomics 55:21-27(1999).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
ELISA 1:40000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-Tyrosine-protein kinase Blk Blk Antibody A01539
Western Blot (WB) analysis of specific cells using Blk polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For BLK (Source: Uniprot.org, NCBI)
Gene Name
BLK
Full Name
Tyrosine-protein kinase Blk
Weight
57.706kDa
Superfamily
protein kinase superfamily
Alternative Names
B lymphocyte kinase; B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase; Blk; EC 2.7.10.2; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk BLK MODY11 BLK proto-oncogene, Src family tyrosine kinase tyrosine-protein kinase Blk|B lymphoid tyrosine kinase|BLK nonreceptor tyrosine kinase|b lymphocyte kinase|p55-Blk
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BLK, check out the BLK Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BLK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Tyrosine-protein kinase Blk Blk Antibody (A01539)
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No publications found for A01539
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