Anti-Tyrosine-protein kinase Blk Blk Monoclonal Antibody

BLK antibody

Boster Bio Anti-Tyrosine-protein kinase Blk Blk Monoclonal Antibody catalog # M01539-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: M01539-1
Size: 100ul
Reactive Species: Human
Host: Mouse
Application: ELISA, IHC, WB

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Product Name

Anti-Tyrosine-protein kinase Blk Blk Monoclonal Antibody

View all BLK Antibodies

SKU/Catalog Number

M01539-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Tyrosine-protein kinase Blk Blk Monoclonal Antibody catalog # M01539-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Tyrosine-protein kinase Blk Blk Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01539-1)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

9D10B7

Isotype

IgG

Immunogen

Purified recombinant fragment of Blk expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M01539-1 is reactive to BLK in Human

Applications

M01539-1 is guaranteed for ELISA, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

57.706kDa

Background of BLK

TRPC6, also known as TRP6, short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6, is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C and may not to be activated by intracellular calcium store depletion. Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS). Expression of this protein has been reported in tissues such as placenta, lung, spleen, ovary, small intestine, and renal podocytes. Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons, breast, respiratory, squamous and prostate epithelium, epidermis, placental trophoblasts, dendritic cells, and subsets of immune cells, and faint to moderate staining of adrenal, colon, ganglion cells, hepatocytes, heart, and testis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000

Validation Images & Assay Conditions

Gene/Protein Information For BLK (Source: Uniprot.org, NCBI)

Gene Name

BLK

Full Name

Tyrosine-protein kinase Blk

Weight

57.706kDa

Superfamily

protein kinase superfamily

Alternative Names

B lymphocyte kinase; B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase; Blk; EC 2.7.10.2; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk BLK MODY11 BLK proto-oncogene, Src family tyrosine kinase tyrosine-protein kinase Blk|B lymphoid tyrosine kinase|BLK nonreceptor tyrosine kinase|b lymphocyte kinase|p55-Blk

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on BLK, check out the BLK Infographic

BLK infographic

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In this infographic, you will see the following information for BLK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01539-1-100ul

100ul

$380

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M01539-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$380.00

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