Product Info Summary
SKU: | A05874 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-UBE2T Antibody
SKU/Catalog Number
A05874
Size
100ul
Form
Liquid
Description
Boster Bio Anti-UBE2T Antibody catalog # A05874. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-UBE2T Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05874)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human DLL3 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05874 is reactive to UBE2T in Human, Mouse, Rat
Applications
A05874 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
22.521kDa
Background of UBE2T
Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.
Nagase T., DNA Res. 5:355-364(1998).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-UBE2T Antibody A05874
Western blot (WB) analysis of UBE2T polyclonal antibody at 1:500 dilutionLane1:MCF-7 whole cell lysate(40ug)
Lane2:HepG2 whole cell lysate(40ug)
Lane3:CT26 whole cell lysate(40ug)
Lane4:C6 whole cell lysate(40ug)
Lane5:H9C2 whole cell lysate(40ug)
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For UBE2T (Source: Uniprot.org, NCBI)
Gene Name
UBE2T
Full Name
Ubiquitin-conjugating enzyme E2 T
Weight
22.521kDa
Superfamily
ubiquitin-conjugating enzyme family
Alternative Names
Cell proliferation-inducing gene 50 protein; EC 6.3.2.19; HSPC150 protein similar to ubiquitin-conjugating enzyme; HSPC150; PIG50; UBE2T; Ubiquitin carrier protein T; ubiquitin conjugating enzyme; ubiquitin-conjugating enzyme E2 T; ubiquitin-conjugating enzyme E2T (putative); Ubiquitin-protein ligase T UBE2T FANCT, HSPC150, PIG50 ubiquitin conjugating enzyme E2 T ubiquitin-conjugating enzyme E2 T|E2 ubiquitin-conjugating enzyme T|HSPC150 protein similar to ubiquitin-conjugating enzyme|cell proliferation-inducing gene 50 protein|ubiquitin carrier protein T|ubiquitin conjugating enzyme E2T|ubiquitin-conjugating enzyme E2T (putative)|ubiquitin-protein ligase T
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on UBE2T, check out the UBE2T Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for UBE2T: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-UBE2T Antibody (A05874)
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No publications found for A05874
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Customer Reviews
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