Product Info Summary
SKU: | A06974 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-UQCRC1 Antibody
SKU/Catalog Number
A06974
Size
100ul
Form
Liquid
Description
Boster Bio Anti-UQCRC1 Antibody catalog # A06974. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-UQCRC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06974)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human BMP10.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06974 is reactive to UQCRC1 in Human, Mouse, Rat
Applications
A06974 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
52.646kDa
Background of UQCRC1
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Celeste A.J., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 434:724-731(2005).
Mazerbourg S., J. Biol. Chem. 280:32122-32132(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For UQCRC1 (Source: Uniprot.org, NCBI)
Gene Name
UQCRC1
Full Name
Cytochrome b-c1 complex subunit 1, mitochondrial
Weight
52.646kDa
Superfamily
peptidase M16 family
Alternative Names
Complex III subunit 1; Core protein I; cytochrome b-c1 complex subunit 1, mitochondrial; D3S3191; QCR1; ubiquinol-cytochrome c reductase core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1; UQCR1 UQCRC1 D3S3191, QCR1, UQCR1 ubiquinol-cytochrome c reductase core protein 1 cytochrome b-c1 complex subunit 1, mitochondrial|complex III subunit 1|core protein I|ubiquinol-cytochrome c reductase core protein I|ubiquinol-cytochrome-c reductase complex core protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on UQCRC1, check out the UQCRC1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for UQCRC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-UQCRC1 Antibody (A06974)
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No publications found for A06974
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