Anti-UQCRC1 Antibody

UQCRC1 antibody

Boster Bio Anti-UQCRC1 Antibody catalog # A06974. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A06974
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-UQCRC1 Antibody

View all UQCRC1 Antibodies

SKU/Catalog Number

A06974

Size

100ul

Form

Liquid

Description

Boster Bio Anti-UQCRC1 Antibody catalog # A06974. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-UQCRC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06974)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from Internal of human BMP10.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06974 is reactive to UQCRC1 in Human, Mouse, Rat

Applications

A06974 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

52.646kDa

Background of UQCRC1

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Celeste A.J., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 434:724-731(2005).
Mazerbourg S., J. Biol. Chem. 280:32122-32132(2005).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200

Validation Images & Assay Conditions

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Gene/Protein Information For UQCRC1 (Source: Uniprot.org, NCBI)

Gene Name

UQCRC1

Full Name

Cytochrome b-c1 complex subunit 1, mitochondrial

Weight

52.646kDa

Superfamily

peptidase M16 family

Alternative Names

Complex III subunit 1; Core protein I; cytochrome b-c1 complex subunit 1, mitochondrial; D3S3191; QCR1; ubiquinol-cytochrome c reductase core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1; UQCR1 UQCRC1 D3S3191, QCR1, UQCR1 ubiquinol-cytochrome c reductase core protein 1 cytochrome b-c1 complex subunit 1, mitochondrial|complex III subunit 1|core protein I|ubiquinol-cytochrome c reductase core protein I|ubiquinol-cytochrome-c reductase complex core protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on UQCRC1, check out the UQCRC1 Infographic

UQCRC1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for UQCRC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A06974-100ul

100ul

$405

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