Anti-Uroplakin 3A (Bladder Carcinoma Marker) Antibody

Product Name

Anti-Uroplakin 3A (Bladder Carcinoma Marker) Antibody

View all Uroplakin III Antibodies

SKU/Catalog Number

M06534

Size

100ug/vial

Form

Liquid

Description

Boster Bio Anti-Uroplakin 3A (Bladder Carcinoma Marker) Antibody (Catalog # M06534). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Cite This Product

Anti-Uroplakin 3A (Bladder Carcinoma Marker) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M06534)

Host

Rabbit

Contents

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Clonality

Polyclonal

Clone Number

Clone: SPM322

Isotype

IgG

Immunogen

A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M06534 is reactive to UPK3A in Human

Applications

M06534 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

30.67kDa

Background of Uroplakin III

Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Reconstitute with distilled water.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Validation Images & Assay Conditions

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Western Blot analysis in human HEK293 lysate in 1) absence and 2) presence of immunizing peptide using Anti-UPK3A Rabbit Polyclonal Antibody.

Gene/Protein Information For UPK3A (Source: Uniprot.org, NCBI)

Alternative Names

MGC119178; UP3a; UPIII; UPIIIA; UPK3; UPK3A; uroplakin 3; uroplakin 3A; Uroplakin III; uroplakin3a; uroplakin-3a UPK3A UP3A, UPIII, UPIIIA, UPK3 uroplakin 3A uroplakin-3a|uroplakin 3|uroplakin III

For more info on UPK3A, check out the UPK3A Infographic

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In this infographic, you will see the following information for UPK3A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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