Product Info Summary
SKU: | A05647-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-VAMP4 Antibody
SKU/Catalog Number
A05647-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-VAMP4 Antibody catalog # A05647-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-VAMP4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05647-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Plakophilin 4
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05647-1 is reactive to VAMP4 in Human, Mouse, Rat
Applications
A05647-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
16.397kDa
Background of VAMP4
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.
Yamakawa A., Gene 202:193-201(1997).
Sillje H.H.W., EMBO J. 18:5691-5702(1999).
Cabaniols J.-P., Mol. Biol. Cell 10:4033-4041(1999).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:200-1:2000
IHC: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For VAMP4 (Source: Uniprot.org, NCBI)
Gene Name
VAMP4
Full Name
Vesicle-associated membrane protein 4
Weight
16.397kDa
Superfamily
synaptobrevin family
Alternative Names
VAMP24; VAMP-4; vesicle-associated membrane protein 4 VAMP4 VAMP-4, VAMP24 vesicle associated membrane protein 4 vesicle-associated membrane protein 4|VAMP4/TAF3 fusion
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on VAMP4, check out the VAMP4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for VAMP4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-VAMP4 Antibody (A05647-1)
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No publications found for A05647-1
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