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Product Info Summary
| SKU: | A00623 |
|---|---|
| Size: | 100μl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-VEGF-C Antibody
SKU/Catalog Number
A00623
Size
100μl
Form
Liquid
Description
Boster Bio Anti-VEGF-C Antibody catalog # A00623. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-VEGF-C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00623)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
8H7
Isotype
IgG
Immunogen
Synthesized peptide derived from the Internal region of human VEGF-C.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00623 is reactive to VEGFC in Human, Mouse, Rat
Applications
A00623 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
46.883kDa
Background of VEGF-C
Binds and is activated by neuregulins and NTAK.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
IHC-P, 1:100-1:300
Validation Images & Assay Conditions
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Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Heart, antibody was diluted at 1:100.
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Western Blot (WB) analysis of L929 cells using VEGF-C Polyclonal antibody.
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Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Heart, antibody was diluted at 1:100.
Protein Target Info & Infographic
Gene/Protein Information For VEGFC (Source: Uniprot.org, NCBI)
Gene Name
VEGFC
Full Name
Vascular endothelial growth factor C
Weight
46.883kDa
Superfamily
PDGF/VEGF growth factor family
Alternative Names
Flt4 ligand; Flt4-L; vascular endothelial growth factor C; Vascular endothelial growth factor-related protein; VEGFC; VEGF-C; VRPFLT4 ligand DHM VEGFC Flt4-L, LMPH1D, LMPHM4, VRP vascular endothelial growth factor C vascular endothelial growth factor C|FLT4 ligand DHM|vascular endothelial growth factor-related protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on VEGFC, check out the VEGFC Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for VEGFC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-VEGF-C Antibody (A00623)
Hello CJ!
A00623 has been cited in 9 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Collagen type V a2 (COL5A2) is decreased in steroid-induced necrosis of the femoral head
HER2 and Src co-regulate proliferation, migration and transformation by downstream signaling pathways in arsenite-treated human uroepithelial cells
Down-regulation of HMGB1 expression by shRNA constructs inhibits the bioactivity of urothelial carcinoma cell lines via the NF-κB pathway
Interleukin-18 suppresses angiogenesis and lymphangiogenesis in implanted Lewis lung cancer
Alternatively activated RAW264.7 macrophages enhance tumor lymphangiogenesis in mouse lung adenocarcinoma
Li,X.,Song,D.,Liu,H.,Wang,Z.,Ma,G.,Yu,M. ... Zeng,Y.(2021).Expression levels of VEGF‑C and VEGFR‑3 in renal cell carcinoma and their association with lymph node metastasis.Experimental and Therapeutic Medicine, 21,554.https://doi.org/10.3892/ etm.2021.9986
Species: Human
A00623 usage in article: APP:IHC, SAMPLE:RCC TISSUE, DILUTION:1:200
Down-regulation of HMGB1 expression by shRNA constructs inhibits the bioactivity of urothelial carcinoma cell lines via the NF-?B pathway
Expression and clinical significance of microRNA-21, maspin and vascular endothelial growth factor-C in bladder cancer
Chen Y, Wang J, Wang X, Liu X, Li H, Lv Q, Zhu J, Wei B, Tang Y. J Breast Cancer. 2013 Mar;16(1):40-9. Doi: 10.4048/Jbc.2013.16.1.40. Epub 2013 Mar 31. Stat3, A Poor Survival Predicator, Is Associated With Lymph Node Metastasis From Breast Cancer.
Recommended Resources
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Customer Reviews
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Customer Q&As
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Find answers in Q&As, reviews.
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5 Customer Q&As for Anti-VEGF-C Antibody
Question
Will anti-VEGF-C antibody A00623 work on dog IHC with layer of synovial tissue?
Verified Customer
Verified customer
Asked: 2019-11-08
Answer
Our lab technicians have not validated anti-VEGF-C antibody A00623 on dog. You can run a BLAST between dog and the immunogen sequence of anti-VEGF-C antibody A00623 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated dog samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in dog layer of synovial tissue in IHC, you can get your next antibody for free.
Boster Scientific Support
Answered: 2019-11-08
Question
Is this A00623 anti-VEGF-C antibody reactive to the isotypes of VEGFC?
Verified Customer
Verified customer
Asked: 2019-08-07
Answer
The immunogen of A00623 anti-VEGF-C antibody is Synthesized peptide derived from the Internal region of human VEGF-C. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2019-08-07
Question
Do you have a BSA free version of anti-VEGF-C antibody A00623 available?
Verified Customer
Verified customer
Asked: 2019-06-17
Answer
I appreciate your recent telephone inquiry. I can confirm that some lots of this anti-VEGF-C antibody A00623 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.
Boster Scientific Support
Answered: 2019-06-17
Question
Here is the WB image, lot number and protocol we used for skin urinary bladder using anti-VEGF-C antibody A00623. Please let me know if you require anything else.
N. Yang
Verified customer
Asked: 2014-03-03
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2014-03-03
Question
We are currently using anti-VEGF-C antibody A00623 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on bovine tissues as well?
D. Williams
Verified customer
Asked: 2013-03-12
Answer
The anti-VEGF-C antibody (A00623) has not been tested for cross reactivity specifically with bovine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in bovine you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2013-03-12
