Anti-VLDL-Receptor (Very Low Density Lipoprotein Receptor) Monoclonal Antibody

Product Name

Anti-VLDL-Receptor (Very Low Density Lipoprotein Receptor) Monoclonal Antibody

View all VLDLR Antibodies

SKU/Catalog Number

M02195

Size

100ug/vial

Form

Liquid

Description

Boster Bio Anti-VLDL-Receptor (Very Low Density Lipoprotein Receptor) Monoclonal Antibody (Catalog # M02195). Tested in IHC applications. This antibody reacts with Human, Rat.

Storage & Handling

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Cite This Product

Anti-VLDL-Receptor (Very Low Density Lipoprotein Receptor) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02195)

Host

Mouse

Contents

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Clonality

Monoclonal

Clone Number

Clone: VLDLR/1337

Isotype

IgG1, lambda

Immunogen

Recombinant human VLDLR fragment from c-terminal

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M02195 is reactive to VLDLR in Human, Rat

Applications

M02195 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

96.098kDa

Background of VLDLR

VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Reconstitute with distilled water.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Validation Images & Assay Conditions

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Formalin-fixed, paraffin-embedded human Pancreas stained with Anti-VLDL-Receptor Mouse Monoclonal Antibody (VLDLR/1337).

Gene/Protein Information For VLDLR (Source: Uniprot.org, NCBI)

Alternative Names

CARMQ1; CHRMQ1; FLJ35024; very low density lipoprotein receptor; very low-density lipoprotein receptor; VLDL R; VLDL receptor; VLDLR; VLDL-R; VLDLRCH VLDLR CAMRQ1, CARMQ1, CHRMQ1, VLDL-RCH, VLDLR very low density lipoprotein receptor very low-density lipoprotein receptor|VLDL receptor

For more info on VLDLR, check out the VLDLR Infographic

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In this infographic, you will see the following information for VLDLR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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