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Product Info Summary
| SKU: | A04941 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-WAC Antibody
SKU/Catalog Number
A04941
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-WAC Antibody (Catalog # A04941). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
WAC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-WAC Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04941)
Host
Rabbit
Contents
WAC Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
WAC antibody was raised against a 19 amino acid peptide near the center of human WAC . The immunogen is located within amino acids 210 - 260 of WAC.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of WAC are known to exist; this antibody will detect the larger isoform.
Reactive Species
A04941 is reactive to WAC in Human, Mouse, Rat
Applications
A04941 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
70.724kDa
Background of WAC
The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WAC Antibody can be used for detection of WAC by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of WAC in human testis tissue lysate with WAC antibody at 1 μg/mL.
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Immunohistochemistry of WAC in mouse testis tissue with WAC antibody at 2.5 μg/ml.
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Immunofluorescence of WAC in mouse testis tissue with WAC antibody at 5 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For WAC (Source: Uniprot.org, NCBI)
Gene Name
WAC
Full Name
WW domain-containing adapter protein with coiled-coil
Weight
70.724kDa
Alternative Names
1110067P07Rik; bA48B24; bA48B24.1; BM-016; FLJ31290; KIAA1844; MGC10753; PRO1741; WW domain containing adaptor with coiled-coil; WW domain-containing adapter protein with coiled-coil; WW domain-containing adaptor with coiled coil; Wwp4 WAC BM-016, DESSH, PRO1741, Wwp4 WW domain containing adaptor with coiled-coil WW domain-containing adapter protein with coiled-coil
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on WAC, check out the WAC Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for WAC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-WAC Antibody (A04941)
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No publications found for A04941
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Customer Reviews
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Customer Q&As
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