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Product Info Summary
| SKU: | A07256 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IHC-P |
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Product info
Product Name
Anti-WDR35 Antibody
SKU/Catalog Number
A07256
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-WDR35 Antibody (Catalog # A07256). Tested in ELISA, IHC-P applications. This antibody reacts with Human.
Storage & Handling
WDR35 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-WDR35 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07256)
Host
Rabbit
Contents
WDR35 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
WDR35 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human WDR35. The immunogen is located within amino acids 60 - 110 of WDR35.
Cross-reactivity
WDR35 antibody is human specific.
Reactive Species
A07256 is reactive to WDR35 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
133.5 kDa
Background of WDR35
WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07256 is guaranteed for ELISA, IHC-P Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WDR35 antibody can be used for detection of WDR35 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Immunohistochemistry of WDR35 in human testis tissue with WDR35 antibody at 5 μg/mL.
Specific Publications For Anti-WDR35 Antibody (A07256)
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