Anti-ZC3H8/Fliz1 Antibody

Product Name

Anti-ZC3H8/Fliz1 Antibody

View all Zc3h8 Antibodies

SKU/Catalog Number

A12985

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-ZC3H8/Fliz1 Antibody (Catalog # A12985). Tested in WB, IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ZC3H8/Fliz1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12985)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human ZC3H8.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12985 is reactive to Zc3h8 in Human

Applications

A12985 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

34.913kDa

Background of Zc3h8

Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene By similarity. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Zhuang D.Z., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Hwang E.S., Immunology 106:464-469(2002).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

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Western blot analysis of extracts from HepG2 cells, using ZC3H8 antibody A12985.

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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ZC3H8 antibody A12985.

Gene/Protein Information For Zc3h8 (Source: Uniprot.org, NCBI)

Alternative Names

Fliz1; ZC3HDC8; zinc finger CCCH domain-containing protein 8; zinc finger CCCH type domain containing 8; zinc finger CCCH-type containing 8; zinc finger CCCH-type domain containing 8

For more info on Zc3h8, check out the Zc3h8 Infographic

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In this infographic, you will see the following information for Zc3h8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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