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Product Info Summary
| SKU: | A09043 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-ZIP10 SLC39A10 Antibody
SKU/Catalog Number
A09043
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ZIP10 SLC39A10 Antibody (Catalog # A09043). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ZIP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ZIP10 SLC39A10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09043)
Host
Rabbit
Contents
ZIP10 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZIP10 antibody was raised against a 17 amino acid synthetic peptide near the center of the human ZIP10. The immunogen is located within amino acids 490 - 540 of ZIP10.
Cross-reactivity
This antibody will not cross-react with the zinc transporter ZIP11.
Reactive Species
A09043 is reactive to SLC39A10 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
94.1 kDa
Background of SLC39A10
ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09043 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZIP10 antibody can be used for detection of ZIP10 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZIP10 in human spleen tissue lysate with ZIP10 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of ZIP10 in human spleen tissue with ZIP10 antibody at 2.5 μg/mL.
Specific Publications For Anti-ZIP10 SLC39A10 Antibody (A09043)
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