Anti-ZIP12 SLC39A12 Antibody

Product Name

Anti-ZIP12 SLC39A12 Antibody

View all SLC39A12 Antibodies

SKU/Catalog Number

A10066

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ZIP12 SLC39A12 Antibody (Catalog # A10066). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

ZIP12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-ZIP12 SLC39A12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10066)

Host

Rabbit

Contents

ZIP12 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

ZIP12 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZIP12. The immunogen is located within the first 50 amino acids of ZIP12.

Cross-reactivity

At least four isoforms of ZIP12 are known to exist. ZIP12 antibody is predicted to not cross-react with other ZIP family members.

Reactive Species

A10066 is reactive to SLC39A12 in Human, Mouse

Observed Molecular Weight

68 kDa

Calculated molecular weight

76.7 kDa

Background of SLC39A12

The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A10066 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ZIP12 antibody can be used for detection of ZIP12 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information SLC39A12

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis