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- Table of Contents
AANAT Antibodies
AND AANAT ELISA kits, AANAT Proteins
Many biological assays use antibodies to detect AANAT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AANAT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AANAT antibodies...
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AANAT Infographic by Boster Bio
All AANAT Products
Product
Figures
Specificity
Applications
Price
Human
WB
$523
Cat # M03784
100 µl
Cat # M03784
100 µl
Human
$628
Cat # LS000015
20 µg, 100 µg
Cat # LS000015
20 µg, 100 µg
AANAT Overview
Facts about Serotonin N-acetyltransferase.
Serotonin N-acetyltransferase (AANAT)
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of dopamine in to N- acetylserotonin, the penultimate step in the synthesis of melatonin.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | AANAT |
| Uniprot: | Q16613 |
| Entrez: | 15 |
Family
| Belongs to: |
|---|
| acetyltransferase family |
Alternative Names
AA-NAT; aralkylamine N-acetyltransferaseEC 2.3.1.87; arylalkylamine N-acetyltransferase; Serotonin acetylase; SNATserotonin N-acetyltransferase
Molecular Weight
Mass (kDA):
23.344 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q25.1 |
| Sequence: | 17; NC_000017.11 (76453351..76470797) |
Tissue Specificity
Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland.
Subcellular Localizations
Cytoplasm.
Diseases
- Pituitary Diseases
- Depressive Disorder
- Diabetes Mellitus
- Neonatal Abstinence Syndrome
- Malignant Neoplasms
- Insulinoma
- Blind Vision
- Retinal Degeneration
- Nervousness
- Neoplasms
- Carcinoma
- Melanosis
Interacting Proteins
- BHLHE40
- MDFI
Pathways
- Circadian Rhythm
- Secretion
- Proteolysis
- Localization
- Insulin Secretion
- Translation
- Rna Interference
- Fertilization
- Neurogenesis
- Phototransduction
- Cell Adhesion
- Photosynthesis
- Immune Response
PTMs
- Phosphorylation
- Acetylation
- Dephosphorylation
Research Areas
- Cancer
- Circadian Rhythm
- Neuroscience
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AANAT
bosterbio.com/bosterbio-gene-info-cards/AANAT
References
PMID: 8661026 by Coon S.L., et al. The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression.
PMID: 11313340 by Coon S.L., et al. cAMP regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation.