ABCB7 Antibodies

AND ABCB7 ELISA kits, ABCB7 Proteins

Many biological assays use antibodies to detect ABCB7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCB7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCB7 antibodies...

We validate the specificity of these antibodies to ABCB7 by testing them on tissues known to express ABCB7 positively and negatively. Browse below to find the ABCB7 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for ABCB7? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ABCB7 IHC Guide

ABCB7 Infographic by Boster Bio

All ABCB7 Products

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Figures

Specificity

Applications

Price

Anti-ABCB7 Antibody

Western blot analysis of extracts of various cell lines, using ABCB7 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded rat heart using ABCB7 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded human gastric cancer using ABCB7 antibody at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A06088-2
100ul

ABCB7 (NM_004299) Human Over-expression Lysate

Human

$628
Cat # LS000022
20 µg, 100 µg

Anti-ABCB7 Antibody

Western blot (WB) analysis of ABCB7 polyclonal antibody at 1:500 dilution
Lane1:Hela cell lysate
Lane2:Raw264

Human, Mouse, Rat

$405
Cat # A06088-1
100ul

ABCB7 Overview

Facts about ATP-binding cassette sub-family B member 7, mitochondrial.

ABCB7 3D structure. Source: alphafold

ATP-binding cassette sub-family B member 7, mitochondrial (ABCB7)

Could be involved in the transport of heme from the mitochondria into the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.

Gene Information

Human
Gene Name:	ABCB7
Uniprot:	O75027
Entrez:	22

Family

Belongs to:

ABC transporter superfamily

Alternative Names

ABC transporter 7 protein; ABC7ATP-binding cassette sub-family B member 7, mitochondrial; ASATATP-binding cassette 7; Atm1p; ATP-binding cassette transporter 7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; EC 3.6.3; EC 3.6.3.42; EST140535

Molecular Weight

Mass (kDA):
82.641 kDA

Genomic Context


Human

Location:	Xq13.3
Sequence:	X; NC_000023.11 (75051048..75156283, complement)

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

Anemia
Sideroblastic Anemia
Hereditary Sideroblastic Anemia
Ataxia
Refractory Anemia With Ringed Sideroblasts
Refractory Anemias
Iron Overload
Cerebellar Ataxia
Friedreich Ataxia
Malignant Neoplasms
Neoplasms
Dysmyelopoietic Syndromes

Hematological Disease
Ataxia, Spinocerebellar
Myopathy
Pearson's Syndrome
Iron Deficiency
Acute Erythroblastic Leukemia
Nerve Degeneration

Pathways

Transport
Pathogenesis
Methylation
Iron-sulfur Cluster Assembly
Protein Maturation
Localization
Cell Death
Heme Transport
Tricarboxylic Acid Cycle
Gene Silencing

Electron Transport
Electron Transport Chain
Oxidative Phosphorylation
Cell Differentiation
Rna Interference

PTMs

Phosphorylation

Methylation

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCB7

References

PMID: 9621516 by Shimada Y., et al. Cloning and chromosomal mapping of a novel ABC transporter gene (hABC7), a candidate for X-linked sideroblastic anemia with spinocerebellar ataxia.

PMID: 10196363 by Allikmets R., et al. Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A).