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- Table of Contents
Facts about Protein AAR2 homolog.
Human | |
---|---|
Gene Name: | AAR2 |
Uniprot: | Q9Y312 |
Entrez: | 25980 |
Belongs to: |
---|
AAR2 family |
AAR2 splicing factor homolog (S. cerevisiae); bA234K24.2; C20orf4; CGI-23; chromosome 20 open reading frame 4; DKFZp564N1363; hypothetical protein LOC25980
Mass (kDA):
43.472 kDA
Human | |
---|---|
Location: | 20q11.23 |
Sequence: | 20; NC_000020.11 (36236136..36256941) |
The AAR2 Marker can be used as a molecular target in a variety of research applications. While many antibodies are available, only a few have the highest affinity for specific target proteins. Boster offers high-affinity secondary antibodies and highly-connectivity DEPs. High-affinity primary antibodies can be highly useful for a variety of applications, including immunohistochemistry and Western blotting.
Boster Bio is the place to go if high-affinity, primary antibodies are what you need. Boster Bio, a specialty antibody manufacturer founded by Steven Xia back in 1993, has over 29,000 publications. Boster Bio's antibodies are highly specific, sensitive, and approved for use in ELISA/Flow Cymetry and IHC. Learn more about Boster Bio.
Flow cytometry is used in a variety of scientific applications. This method uses particles and cells as samples to analyze gene expression. Boster stocks the high-affinity antibodies necessary to make your experiments succeed, regardless of whether they are using human or veterinary samples. Boster's high-affinity prima antibodies are both monoclonal or polyclonal. They have been consistently cited over the past 25 years.
A secondary antibody can recognize an epitope of the primary antibody just like a primary antibody. Using both of these antibodies can enhance sensitivity and reduce cross-reactivity, but there are some challenges involved. For example, the dual-antibody detection method involves an additional incubation step. This method also requires greater optimization to minimize cross reactivity. However, it can provide sensitive results and lower cross-reactivity.
Single B cell sorting is another technique used to isolate high-affinity antibodies from target antigens. Single-cell screening can produce high-affinity antibodies in a matter of weeks. It involves the isolation from viable cells. These cells can often be sourced from immunized or convalescent animals. Then, single cell sorting techniques are used and paired VH/VL antibodies are recovered. Then, the antigens are characterized using gene expression.
Using a proprietary optimization process, the company's Picoband(tm) antibodies are designed to react with target proteins with high affinity. This minimizes cross-reactivity between monoclonal antibodies. Picoband(tm), which is a unique collection, is designed for maximum affinity. These antibodies were derived from the same target, making them an excellent choice in research and development.
Several ELISA tests are performed throughout the antibody development process. One of these tests involves screening each test-bleed after immunization. Afterwards, spleen cells are harvested from animals with the highest response rate. ELISA assays are conducted on positive supernatants. The selected antibodies are then subject to further application testing. To learn more about the benefits of Boster Bio's high-affinity primary antibodies, read the article!
Enzyme-linked immunosorbent assays are similar to other immunoassay technologies, including sandwich ELISA. Both require specific antibodies that bind the target antigen, and a detection device to detect the binding. Boster Bio high-affinity primary antibodies provide researchers with the highest sensitivity possible. They are trusted worldwide by scientists. They are also easy to use. It's easy to see why Boster Bio is the industry leader in this field.
Boster bio products have a high level of purity. Their high-affinity prima antibodies can detect the smallest virus particles. Boster Bio is ISO 9001 accredited, making them suitable for many applications. Contact Boster Bio today for more information about high-affinity antibodies. High-affinity antibodies are the best way for maximum efficiency and effectiveness in the diagnosis and treatment infectious diseases.
To ensure that primary antibodies with the highest affinity are stable and specific, they have been tested. The antibody was immobilized onto Protein A magnetic beads and incubated using biotinylated soluble proteins from CHO cells. The results were compared by flow cytometry with those of control antibodies that share the IgG1 frame. To check for melting temperatures, the antibodies were also evaluated using differential scanning fluorimetry. The data are the average of two independent experiments. The error bars are standard deviations.
Boster Bio high-affinity prima antibodies are able to recognize new strains of influenza. This is one of the main benefits. The antibodies are tetramers made up of alpha, beta, and gamma chains. These chains also include subunits for other Fc-receptors. They can neutralize both an old and a new strain of the influenza virus. Researchers can access these antibodies through a variety research organizations.
PMID: 26527271 by Santos K., et al. Crystallization and biochemical characterization of the human spliceosomal Aar2-Prp8(RNaseH) complex.