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- Table of Contents
Facts about Lysophosphatidylserine lipase ABHD12.
May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and function as a regulator of endocannabinoid signaling pathways. .
| Human | |
|---|---|
| Gene Name: | ABHD12 |
| Uniprot: | Q8N2K0 |
| Entrez: | 26090 |

| Belongs to: |
|---|
| serine esterase family |

ABHD12A; abhydrolase domain containing 12; Abhydrolase domain-containing protein 12; BEM46L2; C20orf22; chromosome 20 open reading frame 22; dJ965G21.2; DKFZP434P106; DKFZp434P106,2-arachidonoylglycerol hydrolase; EC 3.1.1.23; monoacylglycerol lipase ABHD12; PHARC
Mass (kDA):
45.097 kDA

| Human | |
|---|---|
| Location: | 20p11.21 |
| Sequence: | 20; NC_000020.11 (25294743..25390835, complement) |
Endoplasmic reticulum membrane; Single-pass membrane protein.




PMID: 20797687 by Fiskerstrand T., et al. Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism.
PMID: 22969151 by Navia-Paldanius D., et al. Biochemical and pharmacological characterization of human alpha/beta- hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).