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- Table of Contents
Facts about Long-chain-fatty-acid--CoA ligase 3.
Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism.
Human | |
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Gene Name: | ACSL3 |
Uniprot: | O95573 |
Entrez: | 2181 |
Belongs to: |
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ATP-dependent AMP-binding enzyme family |
ACS3EC 6.2.1.3; acyl-CoA synthetase long-chain family member 3; FACL3lignoceroyl-CoA synthase; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; LACS3; Long-chain acyl-CoA synthetase 3; long-chain-fatty-acid--CoA ligase 3; PRO2194
Mass (kDA):
80.42 kDA
Human | |
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Location: | 2q36.1 |
Sequence: | 2; NC_000002.12 (222861036..222944639) |
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
When you are looking for primary antibodies that are highly specific for ACSL3, look no further than Boster Bio. Their high-affinity antibodies are widely used in the research community and have been validated by Western Blotting, Immunohistochemistry, and ELISA methods. Boster antibodies have been used to validate proteins, peptides, and cell lines for over 25 years.
This highly specific antibody targets mutated epitopes of cancer cells. Its antigenicity depends on the amino acid sequence and presence of specific binding motifs. The peptide is designed for immune manipulation of diseased cells using the amino acid sequence. Its composition contains neoantigen peptides or sequences that are immunogenic for a subset of HLA alleles.
PMID: 9177793 by Minekura H., et al. Human acyl-coenzyme A synthetase 3 cDNA and localization of its gene (ACS3) to chromosome band 2q34-q35.
PMID: 11707336 by Minekura H., et al. Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene.