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- Table of Contents
Facts about Long-chain-fatty-acid--CoA ligase 3.
Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism.
| Human | |
|---|---|
| Gene Name: | ACSL3 |
| Uniprot: | O95573 |
| Entrez: | 2181 |

| Belongs to: |
|---|
| ATP-dependent AMP-binding enzyme family |

ACS3EC 6.2.1.3; acyl-CoA synthetase long-chain family member 3; FACL3lignoceroyl-CoA synthase; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; LACS3; Long-chain acyl-CoA synthetase 3; long-chain-fatty-acid--CoA ligase 3; PRO2194
Mass (kDA):
80.42 kDA

| Human | |
|---|---|
| Location: | 2q36.1 |
| Sequence: | 2; NC_000002.12 (222861036..222944639) |
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.





PMID: 9177793 by Minekura H., et al. Human acyl-coenzyme A synthetase 3 cDNA and localization of its gene (ACS3) to chromosome band 2q34-q35.
PMID: 11707336 by Minekura H., et al. Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene.