ACSL3 Antibodies

AND ACSL3 ELISA kits, ACSL3 Proteins

Many biological assays use antibodies to detect ACSL3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACSL3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACSL3 antibodies...

We validate the specificity of these antibodies to ACSL3 by testing them on tissues known to express ACSL3 positively and negatively. Browse below to find the ACSL3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for ACSL3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the ACSL3 Western Blot Guide

ACSL3 Infographic by Boster Bio

All ACSL3 Products

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Product

Figures

Specificity

Applications

Price

Anti-ACSL3 Antibody Picoband®

Western blot analysis of ACSL3 using anti-ACSL3 antibody (A05945)

Human

$370
Cat # A05945
100 μg/vial

ACSL3 (NM_004457) Human Over-expression Lysate

ACSL3 Human Over-expression Lysates NM_004457

Human

$628
Cat # LS002181
20 µg, 100 µg

ACSL3 Overview

Facts about Long-chain-fatty-acid--CoA ligase 3.

ACSL3 3D structure. Source: alphafold

Long-chain-fatty-acid--CoA ligase 3 (ACSL3)

Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity).

Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism.

Gene Information

Human
Gene Name:	ACSL3
Uniprot:	O95573
Entrez:	2181

Family

Belongs to:

ATP-dependent AMP-binding enzyme family

Alternative Names

ACS3EC 6.2.1.3; acyl-CoA synthetase long-chain family member 3; FACL3lignoceroyl-CoA synthase; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; LACS3; Long-chain acyl-CoA synthetase 3; long-chain-fatty-acid--CoA ligase 3; PRO2194

Molecular Weight

Mass (kDA):
80.42 kDA

Genomic Context


Human

Location:	2q36.1
Sequence:	2; NC_000002.12 (222861036..222944639)

Subcellular Localizations

Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Liver Carcinoma
Hepatitis
Prostatic Neoplasms
Diabetes Mellitus, Experimental
Liver Neoplasms
Malignant Neoplasm Of Prostate
Cardiomyopathy, Familial Idiopathic
Cardiomyopathies
Neoplasm Metastasis
Malignant Neoplasm Of Breast

Spermatogenesis Arrest
Hepatitis B
Infertility
Endoplasmic Reticulum Stress
Chlamydia Infections
Hyperlipidemia
Osteoporosis

Pathways

Transport
Fatty Acid Transport
Spermatogenesis
Methylation
Fatty Acid Oxidation
Pathogenesis
Secretion
Cell Development
Dna Methylation
Fatty Acid Beta-oxidation
Spermatid Development
Localization
Demethylation

Senescence
Metabolic Process
Oncogene-induced Senescence
Lipid Storage
Pachytene
Rna Interference
Lipid Metabolic Process

PTMs

Oxidation
Methylation

Phosphorylation
Acylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACSL3

References

PMID: 9177793 by Minekura H., et al. Human acyl-coenzyme A synthetase 3 cDNA and localization of its gene (ACS3) to chromosome band 2q34-q35.

PMID: 11707336 by Minekura H., et al. Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene.