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- Table of Contents
Facts about Beta-adducin.
Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
Human | |
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Gene Name: | ADD2 |
Uniprot: | P35612 |
Entrez: | 119 |
Belongs to: |
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aldolase class II family |
ADDBErythrocyte adducin subunit beta; adducin 2 (beta); beta adducin; beta-adducin
Mass (kDA):
80.854 kDA
Human | |
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Location: | 2p13.3 |
Sequence: | 2; NC_000002.12 (70656784..70768200, complement) |
Expressed mainly in brain, spleen, kidney cortex and medulla, and heart. Also expressed in human umbilical vein endothelial cells, human vascular smooth muscle cells, kidney tubular cells and K-562 cell line.
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
PMID: 1840603 by Joshi R.L., et al. Primary structure and domain organization of human alpha and beta adducin.
PMID: 12951058 by Citterio L., et al. Expression analysis of the human adducin gene family and evidence of ADD2 beta4 multiple splicing variants.