ADRA1A Antibodies

AND ADRA1A ELISA kits, ADRA1A Proteins

Many biological assays use antibodies to detect ADRA1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADRA1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADRA1A antibodies...

We validate the specificity of these antibodies to ADRA1A by testing them on tissues known to express ADRA1A positively and negatively. Browse below to find the ADRA1A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADRA1A Infographic by Boster Bio

All ADRA1A Products

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Anti-alpha 1d Adrenergic Receptor/ADRA1A Antibody Picoband®

3 Q&As

Western blot analysis of ADRA1A using anti-ADRA1A antibody (PB9752)

IHC analysis of ADRA1A using anti-ADRA1A antibody (PB9752)

Human, Mouse, Rat

$370
Cat # PB9752
100 μg/vial

Anti-AR-Alpha 1A (Q365) ADRA1A Antibody

Western blot (WB) analysis of AR-α1A (Q365) pAb at 1:500 dilution
Lane1:HepG2 whole cell lysate(40ug)
Lane2:PC3 whole cell lysate(40ug)
Lane3:LO2 whole cell lysate(40ug)
Lane4:HEK293T whole cell lysate(40ug)

Human

IF, IHC, WB

$405
Cat # A02110
100ul

Anti-ADRA1A Rabbit Monoclonal Antibody

Western blot analysis of ADRA1A using anti-ADRA1A antibody (M02110)

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M02110
100 μl/vial

ADRA1A Overview

Facts about Alpha-1A adrenergic receptor.

ADRA1A 3D structure. Source: alphafold

Alpha-1A adrenergic receptor (ADRA1A)

This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins.

Atomic ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes. .

Gene Information

Human
Gene Name:	ADRA1A
Uniprot:	P35348
Entrez:	148

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

a-1A AdrenergicR; ADRA1A; ADRA1Cadrenergic, alpha-1A-, receptor variant 1; ADRA1L1; adrenergic, alpha -1A-, receptor; adrenergic, alpha-1A-, receptor variant 3; adrenergic, alpha-1A-, receptor variant 5; adrenergic, alpha-1A-, receptor variant 8; adrenergic, alpha-1A-, receptor; adrenergic, alpha-1C-, receptor; alpha-1A Adrenergic R; alpha-1A adrenergic receptor; alpha1A AdrenergicR; Alpha-1A adrenoceptor; Alpha-1A adrenoreceptor; ALPHA1AAR; Alpha-1C adrenergic receptor; Alpha-adrenergic receptor 1c; G protein coupled receptor

Molecular Weight

Mass (kDA):
51.487 kDA

Genomic Context


Human

Location:	8p21.2
Sequence:	8; NC_000008.11 (26738113..26870994, complement)

Tissue Specificity

Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart.

Subcellular Localizations

Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane, caveola. Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.