AFAP1L2 Antibodies

AND AFAP1L2 ELISA kits, AFAP1L2 Proteins

Many biological assays use antibodies to detect AFAP1L2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AFAP1L2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AFAP1L2 antibodies...

We validate the specificity of these antibodies to AFAP1L2 by testing them on tissues known to express AFAP1L2 positively and negatively. Browse below to find the AFAP1L2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for AFAP1L2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the AFAP1L2 IHC Guide

AFAP1L2 Infographic by Boster Bio

All AFAP1L2 Products

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Specificity

Applications

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Anti-AFAP1L2 Antibody

Western blot analysis of AFAP1L2 in mouse liver tissue lysate with AFAP1L2 antibody at (A) 1 and (B) 2 μg/mL

Immunofluorescence of AFAP1L2 in human liver tissue with AFAP1L antibody at 20 μg/mL

Immunohistochemistry of AFAP1L2 in human liver tissue with AFAP1L2 antibody at 2

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A03350
0.1 mg

AFAP1L2 (NM_001001936) Human Over-expression Lysate

AFAP1L2 Human Over-expression Lysates NM_001001936

Human

$628
Cat # LS084632
20 µg, 100 µg

AFAP1L2 (NM_032550) Human Recombinant Protein

Coomassie blue staining of purified AFAP1L2 protein

$1249
Cat # PROTQ8N4X5
20 µg

AFAP1L2 Overview

Facts about Actin filament-associated protein 1-like 2.

AFAP1L2 3D structure. Source: alphafold

Actin filament-associated protein 1-like 2 (AFAP1L2)

May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.

Gene Information

Human
Gene Name:	AFAP1L2
Uniprot:	Q8N4X5
Entrez:	84632

Family

Belongs to:

No superfamily

Alternative Names

actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; AFAP1-like protein 2; FLJ14564; KIAA1914Em:AC005383.4; XB130CTB-1144G6.4

Molecular Weight

Mass (kDA):
91.3 kDA

Genomic Context


Human

Location:	10q25.3
Sequence:	10; NC_000010.11 (114280760..114404778, complement)

Tissue Specificity

Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas.

Subcellular Localizations

Cytoplasm.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Thyroid Neoplasm
Malignant Neoplasm Of Thyroid
Cell Transformation, Neoplastic
Liver Carcinoma
Carcinoma, Papillary
Liver Neoplasms

Papillary Thyroid Carcinoma
Colorectal Cancer
Soft Tissue Neoplasms

Pathways

Cell Proliferation
Cell Death
Cellular Localization
Cell Cycle
Regulation Of Signal Transduction
Localization

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AFAP1L2

References

PMID: 17412687 by Xu J., et al. XB130, a novel adaptor protein for signal transduction.

PMID: 18844995 by Emaduddin M., et al. Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells.