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- Table of Contents
AKAP12 Antibodies
AND AKAP12 ELISA kits, AKAP12 Proteins
Many biological assays use antibodies to detect AKAP12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AKAP12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AKAP12 antibodies...
Designing an IHC experiment for AKAP12? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the AKAP12 IHC GuideAKAP12 Infographic by Boster Bio
All AKAP12 Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02303-3
100 μg/vial
Cat # A02303-3
100 μg/vial
AKAP12 Overview
Facts about A-kinase anchor protein 12.
A-kinase anchor protein 12 (AKAP12)
Anchoring protein which mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC). .
Gene Information
| Human | |
|---|---|
| Gene Name: | AKAP12 |
| Uniprot: | Q02952 |
| Entrez: | 9590 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
A kinase (PRKA) anchor protein (gravin) 12; A kinase (PRKA) anchor protein 12; AKAP 250; AKAP250250kDa; DKFZp686M0430; DKFZp686O0331; FLJ20945; FLJ97621; Gravin; kinase scaffold protein gravin; myasthenia gravis autoantigen gravin; Myasthenia gravis autoantigen
Molecular Weight
Mass (kDA):
191.482 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q25.1 |
| Sequence: | 6; NC_000006.12 (151239815..151358559) |
Tissue Specificity
Expressed in endothelial cells, cultured fibroblasts and osteosarcoma, but not in platelets, leukocytes, monocytic cell lines or peripherical blood cells.
Subcellular Localizations
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Membrane; Lipid-anchor. May be part of the cortical cytoskeleton.
Diseases
- Neoplasms
- Malignant Neoplasms
- Cell Transformation, Neoplastic
- Tissue Adhesions
- Carcinoma
- Neoplasm Metastasis
- Nervousness
- Inflammation
- Tumor Angiogenesis
- Pathologic Neovascularization
- Malignant Squamous Cell Neoplasm
- Colorectal Cancer
- Malignant Neoplasm Of Prostate
Interacting Proteins
- EGFR
Pathways
- Methylation
- Localization
- Dna Methylation
- Cell Adhesion
- Angiogenesis
- Oncogenesis
- Cell Proliferation
- Cell Cycle
- Senescence
- Cytokinesis
- Pathogenesis
- Demethylation
- Cell Death
PTMs
- Phosphorylation
- Methylation
- Myristoylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKAP12
bosterbio.com/bosterbio-gene-info-cards/AKAP12
References
PMID: 9000000 by Nauert J.B., et al. Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein.
PMID: 9604001 by Sato N., et al. Changes of gene expression by lysophosphatidylcholine in vascular endothelial cells: 12 up-regulated distinct genes including 5 cell growth-related, 3 thrombosis-related, and 4 others.
2 Publications of Boster AKAP12 Antibodies & ELISA Kits
- PubMed ID: 10.1007/s10147-019-01604-w, LINC00163 inhibits the invasion and metastasis of gastric cancer cells as a ceRN...
- PubMed ID: 31894433, Zhang J,Piao HY,Guo S,Wang Y,Zhang T,Zheng ZC,Zhao Y.LINC00163 inhibits the inva...
*More publications can be found for each product on its corresponding product page