A-kinase anchor protein 3 Antibodies

AND AKAP3 ELISA kits, A-kinase anchor protein 3 Proteins

Many biological assays use antibodies to detect A-kinase anchor protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with A-kinase anchor protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop A-kinase anchor protein 3 antibodies...

We validate the specificity of these antibodies to A-kinase anchor protein 3 by testing them on tissues known to express AKAP3 positively and negatively. Browse below to find the AKAP3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AKAP3 Infographic by Boster Bio

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Anti-A-kinase anchor protein 3 AKAP3 Antibody

Human, Mouse, Rat

$405
Cat # A07161
100ul

AKAP3 Overview

Facts about A-kinase anchor protein 3.

AKAP3 3D structure. Source: alphafold

A-kinase anchor protein 3 (AKAP3)

May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. .

Gene Information

Human
Gene Name:	AKAP3
Uniprot:	O75969
Entrez:	10566

Family

Belongs to:

AKAP110 family

Alternative Names

A kinase (PRKA) anchor protein 3; AKAP110AKAP 110; AKAP-3; A-kinase anchor protein 110 kDa; Cancer/testis antigen 82; CT82A-kinase anchor protein 3; Fibrous sheath protein of 95 kDa; fibrousheathin 1; Fibrousheathin I; fibrousheathin-1; FSP95A-kinase anchor protein, 110kDa; PRKA3; protein kinase A anchoring protein 3; Protein kinase A-anchoring protein 3; SOB1fibrous sheath protein, 95kDa; sperm oocyte-binding protein 1; Sperm oocyte-binding protein

Molecular Weight

Mass (kDA):
94.751 kDA

Genomic Context


Human

Location:	12p13.32
Sequence:	12; NC_000012.12 (4615508..4649051, complement)

Tissue Specificity

Testis specific; only expressed in spermatids.

Subcellular Localizations

Cytoplasmic vesicle, secretory vesicle, acrosome. Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.

Diseases

Male Infertility
Infertility
Malignant Neoplasms
Neoplasms
Dysplasia
Malignant Neoplasm Of Ovary
Malignant Tumor Of Colon
Malignant Neoplasm Of Lung
Carcinoma
Ovarian Neoplasm
Autoimmunity
Malignant Neoplasm Of Breast

Head And Neck Carcinoma
Aneuploidy
Head And Neck Neoplasms
Dental Plaque
Genital Diseases, Male
Epithelial Ovarian Cancer
Oligospermia

Interacting Proteins

BRAP
PRKAR2A
ROPN1B

Pathways

Sperm Motility
Localization
Acrosome Reaction
Meiosis
Fertilization
Spermatid Development
Spermatogenesis
Sperm Capacitation
Egg Activation
Cell Migration
Cell Development
Germ Cell Development
Swimming

Translation
Phagocytosis
Cell Motility
Regulation Of Sperm Motility
Cell Differentiation
Cell Growth
Pachytene

PTMs

Phosphorylation

Sulphation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKAP3

References

PMID: 10334916 by Lefevre A., et al. Cloning and characterization of SOB1, a new testis-specific cDNA encoding a human sperm protein probably involved in oocyte recognition.

PMID: 10529264 by Mandal A., et al. FSP95, a testis-specific 95-kilodalton fibrous sheath antigen that undergoes tyrosine phosphorylation in capacitated human spermatozoa.