DNA oxidative demethylase ALKBH2 (ALKBH2)

Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA comprising 1- ethenoadenine (in vitro).

Has strong taste for double- stranded DNA. Has low efficiency with single-stranded substrates.