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- Table of Contents
Alsin Antibodies
AND ALS2 ELISA kits, Alsin Proteins
Many biological assays use antibodies to detect Alsin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alsin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alsin antibodies...
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ALS2 Infographic by Boster Bio
All ALS2 Products
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Specificity
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ALS2 Overview
Facts about Alsin.
Alsin (ALS2)
May act as a GTPase regulator.
Controls survival and growth of spinal motoneurons (By similarity).. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ALS2 |
| Uniprot: | Q96Q42 |
| Entrez: | 57679 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ALS2CR6; alsin; ALSJ; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 6; amyotrophic lateral sclerosis 2 (juvenile); Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Amyotrophic lateral sclerosis 2 protein; FLJ31851; IAHSP; KIAA1563; MGC87187; PLSJ
Molecular Weight
Mass (kDA):
183.634 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q33.1 |
| Sequence: | 2; NC_000002.12 (201700267..201781153, complement) |
Diseases
- Sclerosis
- Primary Lateral Sclerosis
- Amyotrophic Lateral Sclerosis
- Motor Neuron Disease
- Spastic Paraplegia, Hereditary
- Neurodegenerative Disorders
- Paraplegia
- Spastic Paraplegia
- Nerve Degeneration
- Neurotoxicity Syndromes
- Atrophy
Interacting Proteins
- RAB5A
Pathways
- Pathogenesis
- Transport
- Localization
- Cell Death
- Endocytosis
- Neuroprotection
- Translation
- Biofilm Formation
- Macropinocytosis
- Microtubule-based Transport
- Virulence
- Mating
- Methylation
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALS2
bosterbio.com/bosterbio-gene-info-cards/ALS2
References
PMID: 11586297 by Yang Y., et al. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis.
PMID: 11586298 by Hadano S., et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.