This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Angiomotin-like protein 2.
Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and thus preventing its translocation to the nucleus. Participates in angiogenesis.
Human | |
---|---|
Gene Name: | AMOTL2 |
Uniprot: | Q9Y2J4 |
Entrez: | 51421 |
Belongs to: |
---|
angiomotin family |
angiomotin like 2; KIAA0989; LCCPangiomotin-like protein 2; Leman coiled-coil protein
Mass (kDA):
85.764 kDA
Human | |
---|---|
Location: | 3q22.2 |
Sequence: | 3; NC_000003.12 (134355345..134375417, complement) |
Recycling endosome.
If you are interested in acquiring an Anti-MRPL15 Antibody, you've come to the right place. Continue reading to learn more about this marker's benefits and uses. This article also contains background information about Steven Boster who created this product. You can also get a free PDF of the boster bio's educational resources, which you can share with your students and colleagues. To do this, you must cite Boster Bio and link to it.
The AMOTL2 marker can be used to study a variety of biological processes, including DNA repair and cancer prevention. The Boster Bio platform offers high-affinity primary antibodies that have been extensively validated on Western Blotting, Immunohistochemistry, and ELISA. Boster Bio's platform is based upon proprietary trade secrets that have been used over 25 years to develop proprietary ELISA kits.
The AMOTL2 Marker is a genetic marker used in the detection of multiple cancers. The gene is expressed in the DA and IVC. A pronounced innate immune response is triggered by the deletion of the gene. Depletion of AmotL2 promotes the induction of adaptive immunity. A dramatic change in the shape of the aortic and nuclear endothelial cells can be seen when this gene is deleted.
Steven Boster passed away on June 26, 2022. He was a Joliet, Illinois native. His father and mother were both soldiers, and he served as a manager in retail sales. He was a Concordia Hall Member of Staunton. His 2 daughters, Crystal Boster (Natosha) and Crystal Peck (Crystal) are his surviving children. He also has six grandkids. He is survived not only by his wife Stevena but also by his 4 brothers Jack, David, Sandy and Sandy Boster. His children Jonathan Boster & Cory Boster, as well as many nieces & nephews, are also survivors.
Steve loved his family the most. However, he also enjoyed auto racing and sport. He was the first person to call when his car broke down at 2 AM. He would always show up, even in the coldest weather. He treated his friends and family with the same generosity he showed to his friends. This generous spirit infused his work and his life with a deep sense of purpose.
PMID: 12406577 by Bratt A., et al. Angiomotin belongs to a novel protein family with conserved coiled- coil and PDZ binding domains.
PMID: 17293535 by Huang H., et al. Amotl2 is essential for cell movements in zebrafish embryo and regulates c-Src translocation.