ANKLE1 Antibodies

AND ANKLE1 ELISA kits, ANKLE1 Proteins

Many biological assays use antibodies to detect ANKLE1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ANKLE1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ANKLE1 antibodies...

We validate the specificity of these antibodies to ANKLE1 by testing them on tissues known to express ANKLE1 positively and negatively. Browse below to find the ANKLE1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ANKLE1 Infographic by Boster Bio

All ANKLE1 Products

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Specificity

Applications

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Anti-ANKLE1 Antibody

Western blot analysis of ANKLE1 in 293 cell lysate with ANKLE1 antibody at (A) 1 and (B) 2 μg/mL

Human, Mouse, Rat

ELISA, WB

$481
Cat # A14094
0.1 mg

ANKLE1 (NM_152363) Human Over-expression Lysate

Human

$960
Cat # LS126549
20 µg, 100 µg

ANKLE1 Overview

Facts about Ankyrin repeat and LEM domain-containing protein 1.

ANKLE1 3D structure. Source: alphafold

Ankyrin repeat and LEM domain-containing protein 1 (ANKLE1)

Endonuclease that likely plays a role in the DNA damage response and DNA repair. .

Gene Information

Human
Gene Name:	ANKLE1
Uniprot:	Q8NAG6
Entrez:	126549

Family

Belongs to:

No superfamily

Alternative Names

ANKRD41; ankyrin repeat and LEM domain containing 1; ankyrin repeat and LEM domain-containing protein 1; FLJ39369; LEM domain containing 6; LEMD6; LEM-domain containing protein 3

Molecular Weight

Mass (kDA):
66.89 kDA

Genomic Context


Human

Location:	19p13.11
Sequence:	19; NC_000019.10 (17281901..17287646)

Tissue Specificity

Expression is predominant in adult bone marrow.

Subcellular Localizations

Cytoplasm. Nucleus. At the steady state, localizes predominantly in the cytoplasm.

PTMs

Cleavage

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANKLE1

References

PMID: 22399800 by Brachner A., et al. The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo.

PMID: 27245214 by Zlopasa L., et al. Nucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signals.