Anti-ANKLE1 Antibody

LEM3 antibody

Boster Bio Anti-ANKLE1 Antibody (Catalog # A14094). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A14094
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Chicken
Application: ELISA, WB

Product Name

Anti-ANKLE1 Antibody

View all LEM3 Antibodies

SKU/Catalog Number

A14094

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ANKLE1 Antibody (Catalog # A14094). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

ANKLE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-ANKLE1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14094)

Host

Chicken

Contents

ANKLE1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgY

Immunogen

ANKLE1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ANKLE1. The immunogen is located within the last 50 amino acids of ANKLE1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Two isoforms of ANKLE1 are known to exist. ANKLE1 antibody is predicted to not cross-react with ANKLE2

Reactive Species

A14094 is reactive to ANKLE1 in Human, Mouse, Rat

Applications

A14094 is guaranteed for ELISA, WB Boster Guarantee

Background of LEM3

Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE1 (Ankyrin repeat and LEM domain containing 1) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. While the function of this protein is still under investigation, its gene locus has been associated with susceptibility to ovarian and breast cancer.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

ANKLE1 antibody can be used for detection of ANKLE1 by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Validation Images & Assay Conditions

Gene/Protein Information For ANKLE1 (Source: Uniprot.org, NCBI)

Uniprot ID

Q8NAG6

Gene ID

126549

Gene Name

ANKLE1

Full Name

Ankyrin repeat and LEM domain-containing protein 1

Weight

66.89kDa

Alternative Names

ANKRD41; ankyrin repeat and LEM domain containing 1; ankyrin repeat and LEM domain-containing protein 1; FLJ39369; LEM domain containing 6; LEMD6; LEM-domain containing protein 3 ANKLE1 ANKRD41, LEM3, LEMD6 ankyrin repeat and LEM domain containing 1 ankyrin repeat and LEM domain-containing protein 1|LEM domain containing 6|LEM-domain containing 3|ankyrin repeat domain-containing protein 41

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ANKLE1, check out the ANKLE1 Infographic

ANKLE1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ANKLE1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Ships directly to USA and Canada. For other regions, visit our distributors page

Bulk Inquiry

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A14094
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$404.00

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