ANKRD2 Antibodies

AND ANKRD2 ELISA kits, ANKRD2 Proteins

Many biological assays use antibodies to detect ANKRD2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ANKRD2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ANKRD2 antibodies...

We validate the specificity of these antibodies to ANKRD2 by testing them on tissues known to express ANKRD2 positively and negatively. Browse below to find the ANKRD2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ANKRD2 Infographic by Boster Bio

All ANKRD2 Products

Product

Figures

Specificity

Applications

Price

ANKRD2 (NM_001129981) Human Recombinant Protein

$1249
Cat # PROTQ9GZV1
20 µg

ANKRD2 (NM_020349) Human Over-expression Lysate

Human

$628
Cat # LS026287
100 µg

ANKRD2 Overview

Facts about Ankyrin repeat domain-containing protein 2.

ANKRD2 3D structure. Source: alphafold

Ankyrin repeat domain-containing protein 2 (ANKRD2)

Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle strain.

Gene Information

Human
Gene Name:	ANKRD2
Uniprot:	Q9GZV1
Entrez:	26287

Family

Belongs to:

No superfamily

Alternative Names

ankyrin repeat domain 2 (stretch responsive muscle); ankyrin repeat domain-containing protein 2; ankyrin-repeat protein; ARPPSkeletal muscle ankyrin repeat protein; hArpp; MGC104314

Molecular Weight

Mass (kDA):
39.859 kDA

Genomic Context


Human

Location:	10q24.2
Sequence:	10; NC_000010.11 (97572441..97583884)

Tissue Specificity

Mostly expressed in skeletal and cardiac muscles. Found in slow fibers. Also expressed in kidney, but to a lower extent (at protein level).

Subcellular Localizations

Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, cytosol. Nucleus. Nucleus, PML body. In the sarcoplasm of differentiated striated muscle cells, where it is cytosolic and enriched in the I band. In nucleus and PML bodies of proliferating and undifferentiated myoblasts. Associates with the euchromatin in the nucleus of myocytes upon muscle stress.

Diseases

Hypertrophy
Muscular Dystrophy
Cardiac Hypertrophy
Neoplasms
Muscle Injury
Dystrophy
Muscular Atrophy
Carcinoma
Atrophy
Rhabdomyosarcoma
Diabetes Mellitus
Leiomyosarcoma

Muscular Dystrophy, Animal
Sclerosis
Primary Lateral Sclerosis
Neuromuscular Diseases
Kidney Neoplasm
Amyotrophic Lateral Sclerosis
Sarcoma

Pathways

Localization
Regulation Of Gene Expression
Muscle Hypertrophy
Cell Cycle
Regulation Of Muscle Hypertrophy
Skeletal Muscle Hypertrophy
Response To Stress
Muscle Cell Differentiation
Aging
Striated Muscle Hypertrophy
Proteolysis
Endocytosis

Autolysis
Inflammatory Response
Regeneration
Translation
Cell Differentiation
Innervation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANKRD2

References

PMID: 11444853 by Pallavicini A., et al. Characterization of human skeletal muscle Ankrd2.

PMID: 14583192 by Miller M.K., et al. The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules.