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Product Info Summary
| SKU: | A07999-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-KANK2 Antibody
SKU/Catalog Number
A07999-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-KANK2 Antibody (Catalog # A07999-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
KANK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-KANK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07999-1)
Host
Rabbit
Contents
KANK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
KANK2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human KANK2 . The immunogen is located within the last 50 amino acids of KANK2.
Cross-reactivity
Two alternatively spliced transcript variants encoding different isoforms have been identified.
Reactive Species
A07999-1 is reactive to KANK2 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
91.2 kDa
Background of KANK2
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK2 (KN motif and ankyrin repeat domain-containing protein 2), was initially identified as a steroid receptor coactivator (SRC) interacting protein (SIP) that could sequester steroid receptor coactivators in the cytoplasm. More recent experiments have shown that while KANK2 is widely expressed, in kidney podocytes, KANK2 localizes to foot processes, suggesting that KANK2 may contribute to controlling actin dynamics in podocyte foot processes.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07999-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KANK2 Antibody can be used for detection of KANK2 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of KANK2 in mouse brain tissue lysate with KANK2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of KANK2 in human kidney tissue with KANK2 antibody at 2.5 μg/ml.
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Immunofluorescence of KANK2 in human kidney tissue with KANK2 antibody at 20 μg/ml.
Specific Publications For Anti-KANK2 Antibody (A07999-1)
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