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- Table of Contents
Facts about Acidic leucine-rich nuclear phosphoprotein 32 family member B.
Anti-apoptotic protein that acts as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity).
Human | |
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Gene Name: | ANP32B |
Uniprot: | Q92688 |
Entrez: | 10541 |
Belongs to: |
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ANP32 family |
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B; acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; APRILSilver-stainable protein SSP29; PHAPI2SSP29; Putative HLA-DR-associated protein I-2
Mass (kDA):
28.788 kDA
Human | |
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Location: | 9q22.33 |
Sequence: | 9; NC_000009.12 (97983341..98015943) |
Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.
[Isoform 1]: Nucleus. Accumulates in the nuclei at the S phase.; [Isoform 2]: Cytoplasm. Lacks a nuclear localization signal.
PMID: 9473664 by Mencinger M., et al. Expression analysis and chromosomal mapping of a novel human gene, APRIL, encoding an acidic protein rich in leucines.
PMID: 15895553 by Matilla A., et al. The Anp32 family of proteins containing leucine-rich repeats.