AOC2 Antibodies

AND AOC2 ELISA kits, AOC2 Proteins

Many biological assays use antibodies to detect AOC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AOC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AOC2 antibodies...

We validate the specificity of these antibodies to AOC2 by testing them on tissues known to express AOC2 positively and negatively. Browse below to find the AOC2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: A1BG Next: AOX1

AOC2 Infographic by Boster Bio

All AOC2 Products

Product

Figures

Specificity

Applications

Price

AOC2 (NM_001158) Human Over-expression Lysate

Human

$960
Cat # LS000314
100 µg

AOC2 Overview

Facts about Retina-specific copper amine oxidase.

AOC2 3D structure. Source: alphafold

Retina-specific copper amine oxidase (AOC2)

Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis.

May be a critical modulator of signal transmission . .

Gene Information

Human
Gene Name:	AOC2
Uniprot:	O75106
Entrez:	314

Family

Belongs to:

copper/topaquinone oxidase family

Alternative Names

Amine oxidase [copper-containing]; amine oxidase, copper containing 2 (retina-specific); AOC2; DAO2; EC 1.4.3; RAO; RAOEC 1.4.3.21; retina-specific copper amine oxidase; Semicarbazide-sensitive amine oxidase; SSAO

Molecular Weight

Mass (kDA):
83.673 kDA

Genomic Context


Human

Location:	17q21.31
Sequence:	17; NC_000017.11 (42844580..42850707)

Tissue Specificity

Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis.

Subcellular Localizations

[Isoform 1]: Cell membrane; Peripheral membrane protein. Present on the surface of the cells.; [Isoform 2]: Cytoplasm. Either not translocated to the plasma membrane or below detection level.

Diseases

Tissue Adhesions
Obesity
Simpson-golabi-behmel Syndrome, Type 1
Retinitis Pigmentosa
Retinal Diseases
Sterility

Visceral Obesity

Pathways

Senescence
Leaf Senescence
Flower Development
Localization
Defense Response
Leaf Development

PTMs

Oxidation

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AOC2

References

PMID: 9119395 by Imamura Y., et al. Human retina-specific amine oxidase (RAO): cDNA cloning, tissue expression, and chromosomal mapping.

PMID: 9722954 by Imamura Y., et al. Human retina-specific amine oxidase: genomic structure of the gene (AOC2), alternatively spliced variant, and mRNA expression in retina.