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- Table of Contents
Facts about AP-3 complex subunit delta-1.
It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation (PubMed:26744459).
Human | |
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Gene Name: | AP3D1 |
Uniprot: | O14617 |
Entrez: | 8943 |
Belongs to: |
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adaptor complexes large subunit family |
Adapter-related protein complex 3 subunit delta-1; adaptin, delta; adaptor-related protein complex 3, delta 1 subunit; ADTD; AP-3 complex delta subunit, partial CDS; AP-3 complex subunit delta; AP-3 complex subunit delta-1; delta adaptin; Delta-adaptin; delta-adaptin, partial CDS; hBLVR; subunit of putative vesicle coat adaptor complex AP-3
Mass (kDA):
130.158 kDA
Human | |
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Location: | 19p13.3 |
Sequence: | 19; NC_000019.10 (2100988..2151566, complement) |
Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis.
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
PMID: 9303295 by Ooi C.E., et al. Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet.
PMID: 9151686 by Simpson F., et al. Characterization of the adaptor-related protein complex, AP-3.