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- Table of Contents
Apolipoprotein A-I Antibodies
AND APOA1 ELISA kits, Apolipoprotein A-I Proteins
Many biological assays use antibodies to detect Apolipoprotein A-I, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Apolipoprotein A-I in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Apolipoprotein A-I antibodies...
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APOA1 Infographic by Boster Bio
All APOA1 Products
Product
Figures
Specificity
Applications
Price
Anti-Apolipoprotein A I/APOA1 Antibody Picoband®
1 Citations
Mouse
IHC, WB
$370
Cat # PB9844
100 μg/vial
Cat # PB9844
100 μg/vial
Human APOA1/Apolipoprotein A-I ELISA Kit PicoKine®
1 Citations 10 Q&As
Human
ELISA
$499
Cat # EK1456
96 wells/kit, with removable strips.
Cat # EK1456
96 wells/kit, with removable strips.
Anti-Apolipoprotein A I/APOA1 Antibody Picoband®
1 Citations 1 Q&As
Human
Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9916
100 μg/vial
Cat # PB9916
100 μg/vial
Human
WB, ELISA (Cap)
$370
Cat # M00717-1
100 μg/vial
Cat # M00717-1
100 μg/vial
Human
ELISA
$500
Cat # EZ1456
For 5 plates, 96 wells each
Cat # EZ1456
For 5 plates, 96 wells each
Human
ELISA
$499
Cat # FEK1456
96 wells/kit, with removable strips.
Cat # FEK1456
96 wells/kit, with removable strips.
Human
$628
Cat # LS000335
20 µg, 100 µg
Cat # LS000335
20 µg, 100 µg
Human
IP, IF, IHC, ICC, WB
$370
Cat # M00717-2
100 μl/vial
Cat # M00717-2
100 μl/vial
APOA1 Overview
Facts about Apolipoprotein A-I.
Apolipoprotein A-I (APOA1)
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | APOA1 |
| Uniprot: | P02647 |
| Entrez: | 335 |
Family
| Belongs to: |
|---|
| apolipoprotein A1/A4/E family |
Alternative Names
Alp-1; APOA1; Apo-AI; apoA-I; Apolipoprotein A1; Apolipoprotein AI; Apolipoprotein A-I; Brp-14; Ltw-1; Lvtw-1; MGC117399; Sep-1; Sep-2
Molecular Weight
Mass (kDA):
30.778 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q23.3 |
| Sequence: | 11; NC_000011.10 (116835751..116837950, complement) |
Tissue Specificity
Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease.
Subcellular Localizations
Secreted.
Diseases
- Atherosclerosis
- Cardiovascular Diseases
- Diabetes Mellitus
- Coronary Heart Disease
- Obesity
- Dyslipidemias
- Coronary Artery Disease
- Heart Diseases
- Hyperlipidemia
- Hypertensive Disease
- Inflammation
- Hypercholesterolemia
Interacting Proteins
- ABCA1
- APP
- CMTM5
- FGA
- HP
- LCAT
Pathways
- Transport
- Cholesterol Efflux
- Cholesterol Transport
- Reverse Cholesterol Transport
- Secretion
- Pathogenesis
- Cholesterol Homeostasis
- Excretion
- Coagulation
- Aging
- Lipid Transport
- Localization
- Inflammatory Response
PTMs
- Oxidation
- Phosphorylation
- Cleavage
- Glycosylation
- Acetylation
Research Areas
- Biologically Active Proteins
- Breast Cancer
- Cancer
- Diabetes Research
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APOA1
bosterbio.com/bosterbio-gene-info-cards/APOA1
References
PMID: 6406984 by Shoulders C.C., et al. Gene structure of human apolipoprotein A1.
PMID: 6304641 by Cheung P., et al. Nucleotide sequence of cloned cDNA of human apolipoprotein A-I.
4 Publications of Boster Apolipoprotein A-I Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.jprot.2020.104098, Rapid glycosylation analysis of mouse serum glycoproteins separated by supported...
- PubMed ID: 34103620, Xiang Y,Zheng Y,Liu S,Liu G,Li Z,Dong W.Comparison of the sensitivity of Western...
- PubMed ID: 26053398, Detection of Serum Protein Biomarkers for the Diagnosis and Staging of Hepatobla...
- PubMed ID: 29618920, Ding N, Luo S, Yu J, Zhou Y, Wu Z. Mol Vis. 2018 Mar 26;24:252-260. eCollection ...
*More publications can be found for each product on its corresponding product page