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- Table of Contents
6 Citations 8 Q&As
1 Citations 7 Q&As
1 Citations 5 Q&As
Facts about Amphiregulin.
Ligand of the EGF receptor/EGFR.
Autocrine growth factor in addition to a mitogen for a broad selection of target cells including astrocytes, Schwann cells and fibroblasts..
| Human | |
|---|---|
| Gene Name: | AREG |
| Uniprot: | P15514 |
| Entrez: | 374 |

| Belongs to: |
|---|
| amphiregulin family |

Amphiregulin; AR; AREG; AREGB; Colorectum cell-derived growth factor; CRDGF; MGC13647; schwannoma-derived growth factor; SDGF
Mass (kDA):
27.895 kDA

| Human | |
|---|---|
| Location: | 4q13.3 |
| Sequence: | 4; NC_000004.12 (74445136..74455005) |
Membrane; Single-pass membrane protein.





PMID: 2325643 by Plowman G.D., et al. The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity.
PMID: 2466334 by Shoyab M., et al. Structure and function of human amphiregulin: a member of the epidermal growth factor family.
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