ARHGDIB Antibodies

AND ARHGDIB ELISA kits, ARHGDIB Proteins

Many biological assays use antibodies to detect ARHGDIB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARHGDIB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARHGDIB antibodies...

We validate the specificity of these antibodies to ARHGDIB by testing them on tissues known to express ARHGDIB positively and negatively. Browse below to find the ARHGDIB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARHGDIB Infographic by Boster Bio

All ARHGDIB Products

Product

Figures

Specificity

Applications

Price

Anti-ARHGDIB Antibody

Human, Mouse

$405
Cat # A03461
100ul

Human ARHGDIB Recombinant Protein

SDS-PAGE

$350
Cat # PROTP52566
Starting from 10ug

D4 (ARHGDIB) (NM_001175) Human Over-expression Lysate

Human

$628
Cat # LS000397
100 µg

ARHGDIB Overview

Facts about Rho GDP-dissociation inhibitor 2.

ARHGDIB 3D structure. Source: alphafold

Rho GDP-dissociation inhibitor 2 (ARHGDIB)

Regulates the GDP/GTP exchange response of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).

Gene Information

Human
Gene Name:	ARHGDIB
Uniprot:	P52566
Entrez:	397

Family

Belongs to:

Rho GDI family

Alternative Names

ARHGDIB Rho GDP dissociation inhibitor (GDI) beta ; D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; RhoGDI2

Molecular Weight

Mass (kDA):
22.988 kDA

Genomic Context


Human

Location:	12p12.3
Sequence:	12; NC_000012.12 (14942015..14961601, complement)

Tissue Specificity

Detected in bone marrow, thymus and spleen.

Subcellular Localizations

Cytoplasm, cytosol.

Diseases

Malignant Neoplasms
Neoplasm Metastasis
Neoplasms
Malignant Neoplasm Of Urinary Bladder
Bladder Neoplasm
Neoplasm Invasiveness
Cell Invasion
Lung Neoplasms
Carcinoma
Metastatic Malignant Neoplasm To The Lung
Malignant Neoplasm Of Breast
Malignant Paraganglionic Neoplasm

Mammary Neoplasms
Carcinoma, Transitional Cell
Tissue Adhesions
Leukemia
Stomach Neoplasms
Melanoma

Pathways

Cell Death
Cell Motility
Drug Resistance
Programmed Cell Death
Flight
Induction Of Apoptosis
Localization
Anoikis
Rna Interference
Cell Migration
Stem Cell Differentiation
Proteolysis
Immune Response

Superoxide Anion Generation
Nuclear Export
Inflammatory Response
Chemotaxis
Translation
Phagocytosis
Cell Cycle

PTMs

Cleavage
Phosphorylation

Hydroxylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARHGDIB

References

PMID: 8356058 by Scherle P., et al. Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes.

PMID: 8262133 by Leffers H., et al. Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton.