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- Table of Contents
Facts about Rho guanine nucleotide exchange factor 3.
Human | |
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Gene Name: | ARHGEF3 |
Uniprot: | Q9NR81 |
Entrez: | 50650 |
Belongs to: |
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No superfamily |
DKFZP434F2429; Exchange factor found in platelets and leukemic and neuronal tissues; FLJ98126; MGC118905; Rho guanine nucleotide exchange factor (GEF) 3; rho guanine nucleotide exchange factor 3,59.8 kDA protein; RhoGEF protein; XPLNXPLN
Mass (kDA):
59.783 kDA
Human | |
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Location: | 3p14.3 |
Sequence: | 3; NC_000003.12 (56727419..57079308, complement) |
Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney.
Cytoplasm.
PMID: 10873612 by Thiesen S., et al. Isolation of two novel human RhoGEFs, ARHGEF3 and ARHGEF4, in 3p13-21 and 2q22.
PMID: 12221096 by Arthur W.T., et al. XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.