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ARHGEF3 Antibodies
AND ARHGEF3 ELISA kits, ARHGEF3 Proteins
Many biological assays use antibodies to detect ARHGEF3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARHGEF3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARHGEF3 antibodies...
Designing an IHC experiment for ARHGEF3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ARHGEF3 IHC GuideARHGEF3 Infographic by Boster Bio
All ARHGEF3 Products
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ARHGEF3 Overview
Facts about Rho guanine nucleotide exchange factor 3.
Rho guanine nucleotide exchange factor 3 (ARHGEF3)
Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ARHGEF3 |
| Uniprot: | Q9NR81 |
| Entrez: | 50650 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DKFZP434F2429; Exchange factor found in platelets and leukemic and neuronal tissues; FLJ98126; MGC118905; Rho guanine nucleotide exchange factor (GEF) 3; rho guanine nucleotide exchange factor 3,59.8 kDA protein; RhoGEF protein; XPLNXPLN
Molecular Weight
Mass (kDA):
59.783 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p14.3 |
| Sequence: | 3; NC_000003.12 (56727419..57079308, complement) |
Tissue Specificity
Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney.
Subcellular Localizations
Cytoplasm.
Diseases
- Osteoporosis
- Total Intestinal Aganglionosis
- Anemia
- Hypochromic Anemia
- Infarction
- Teratocarcinoma
- Iron Deficiency Anemia
- Arthritis
- Metabolic Diseases
- Fracture
- Osteoporosis, Postmenopausal
- Metabolic Syndrome X
Interacting Proteins
- CEP70
- TRIM23
- TRIM27
Pathways
- Peristalsis
- Platelet Activation
- Neurogenesis
- Cell Maturation
PTMs
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARHGEF3
bosterbio.com/bosterbio-gene-info-cards/ARHGEF3
References
PMID: 10873612 by Thiesen S., et al. Isolation of two novel human RhoGEFs, ARHGEF3 and ARHGEF4, in 3p13-21 and 2q22.
PMID: 12221096 by Arthur W.T., et al. XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.