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- Table of Contents
Facts about ADP-ribosylation factor-like protein 13B.
Binds GTP but isn't able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube.
| Mouse | |
|---|---|
| Gene Name: | Arl13b |
| Uniprot: | Q640N2 |
| Entrez: | 68146 |

| Belongs to: |
|---|
| small GTPase superfamily |

ADP-ribosylation factor-like 13B; ADP-ribosylation factor-like 2-like 1; ADP-ribosylation factor-like protein 13B; ADP-ribosylation factor-like protein 2-like 1; ARL2L1MGC120611; ARL2-like protein 1; DKFZp686E2075; DKFZp686L2472; DKFZp761H079; JBTS8DKFZp686M2074; MGC120612
Mass (kDA):
48.144 kDA

| Mouse | |
|---|---|
| Location: | 16|16 C1.3 |
| Sequence: | 16; |
Cilium-specific protein. Expressed in neuroepithelial cells and developing radial glia of the developing cerebral cortex: present in both neuroepithelial and radial progenitor cells. In radial progenitors, found in the apical, cell soma domains of these cells (at protein level). Expressed in the primary cilia of postmitotic cortical neurons during embryonic and postnatal development.



PMID: 17488627 by Caspary T., et al. The graded response to Sonic Hedgehog depends on cilia architecture.
PMID: 20643351 by Kinzel D., et al. Pitchfork regulates primary cilia disassembly and left-right asymmetry.