ADP-ribosylation factor-like protein 2 (ARL2)

Small GTP-binding protein that cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit.

Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction.