ASAP2 Antibodies

AND ASAP2 ELISA kits, ASAP2 Proteins

Many biological assays use antibodies to detect ASAP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ASAP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ASAP2 antibodies...

We validate the specificity of these antibodies to ASAP2 by testing them on tissues known to express ASAP2 positively and negatively. Browse below to find the ASAP2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ASAP2 Infographic by Boster Bio

All ASAP2 Products

Product

Figures

Specificity

Applications

Price

Anti-ASAP2/Pag3 Antibody

1 Q&As

Human

$341
Cat # A09026
100 µg

Anti-ASAP2 Antibody

Human, Mouse, Rat

$405
Cat # A09026-1
100ul

PAG3 (ASAP2) (NM_003887) Human Over-expression Lysate

Human

$960
Cat # LS008853
100 µg

ASAP2 Overview

Facts about Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2.

ASAP2 3D structure. Source: alphafold

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2)

Activates the small GTPases ARF1, ARF5 and ARF6.
Regulates the formation of post-Golgi vesicles and modulates constitutive secretion.

Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration.

Gene Information

Human
Gene Name:	ASAP2
Uniprot:	O43150
Entrez:	8853

Family

Belongs to:

No superfamily

Alternative Names

arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; ArfGAP with SH3 domain, ankyrin repeat and PH domain 2; centaurin, beta 3; CENTB3; DDEF2FLJ42910; development and differentiation enhancing factor 2; Development and differentiation-enhancing factor 2; KIAA0400AMAP2; Pap-alpha; PAPPAG3; Paxillin-associated protein with ARF GAP activity 3; PYK2 C terminus-associated protein; Pyk2 C-terminus-associated protein; SHAG1

Molecular Weight

Mass (kDA):
111.651 kDA

Genomic Context


Human

Location:	2p25.1\|2p24
Sequence:	2; NC_000002.12 (9206765..9405683)

Tissue Specificity

Detected in heart, brain, placenta, kidney, monocytes and pancreas.

Subcellular Localizations

Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Colocalizes with F-actin and ARF6 in phagocytic cups.

Diseases

Tissue Adhesions
Malignant Neoplasms
Neoplasms
Cell Invasion
Malignant Neoplasm Of Prostate
Neoplasm Metastasis
Escherichia Coli Infections
Lung Neoplasms
Metastatic Malignant Neoplasm To The Lymph Node
Non-small Cell Lung Carcinoma
Neoplasm Invasiveness
Experimental Autoimmune Encephalomyelitis
Carcinogenesis

Lymphatic Metastasis
Prostatic Neoplasms
Colorectal Neoplasms
Diarrhea
Colorectal Cancer
Cattle Diseases
Atypical Small Acinar Proliferation Of The Prostate Gland

Interacting Proteins

GRB2
PLCG1
UBC

Pathways

Cell Migration
Cell Adhesion
Protein Phosphorylation
Regeneration
Phagocytosis
Cell Cycle
Endocytosis
Virulence

Localization
Endothelial Cell-cell Adhesion
Cell-cell Adhesion

PTMs

Phosphorylation

Ribosylation

Research Areas

Cell Biology
Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ASAP2

References

PMID: 10022920 by Andreev J., et al. Identification of a new Pyk2 target protein with Arf-GAP activity.

PMID: 10749932 by Kondo A., et al. A new paxillin-binding protein, PAG3/Papalpha/KIAA0400, bearing an ADP-ribosylation factor GTPase-activating protein activity, is involved in paxillin recruitment to focal adhesions and cell migration.