Achaete-scute homolog 2 Antibodies

AND ASCL2 ELISA kits, Achaete-scute homolog 2 Proteins

Many biological assays use antibodies to detect Achaete-scute homolog 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Achaete-scute homolog 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Achaete-scute homolog 2 antibodies...

We validate the specificity of these antibodies to Achaete-scute homolog 2 by testing them on tissues known to express ASCL2 positively and negatively. Browse below to find the ASCL2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ASCL2 Infographic by Boster Bio

All ASCL2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Mash2 ASCL2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A05155-1
100ul

ASCL2 (NM_005170) Human Recombinant Protein

Coomassie blue staining of purified ASCL2 protein

$1249
Cat # PROTQ99929
20 µg

ASCL2 (NM_005170) Human Over-expression Lysate

Human

$628
Cat # LS000430
20 µg, 100 µg

ASCL2 Overview

Facts about Achaete-scute homolog 2.

ASCL2 3D structure. Source: alphafold

Achaete-scute homolog 2 (ASCL2)

AS-C proteins are included in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. .

Gene Information

Human
Gene Name:	ASCL2
Uniprot:	Q99929
Entrez:	430

Family

Belongs to:

No superfamily

Alternative Names

achaete-scute complex (Drosophila) homolog-like 2; achaete-scute complex homolog 2 (Drosophila); achaete-scute complex-like 2 (Drosophila); ASCL2; ASH2; ASH-2; BHLHA45; bHLHa45achaete-scute homolog 2; Class A basic helix-loop-helix protein 45; HASH2; HASH2achaete-scute complex-like 2; mammalian achaete/scute homologue 2; Mash2

Molecular Weight

Mass (kDA):
20.185 kDA

Genomic Context


Human

Location:	11p15.5
Sequence:	11; NC_000011.10 (2268498..2270952, complement)

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Colorectal Neoplasms
Beckwith-wiedemann Syndrome
Hypoxia
Fetal Growth Retardation
Colorectal Cancer
Cell Invasion
Hyperplasia
Neoplasm Metastasis
Adenoma
Metastatic Malignant Neoplasm To The Liver
Malignant Tumor Of Colon

Carcinoma
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Fetal Death
Cell Transformation, Neoplastic
Tetraploidy
Neoplasm Invasiveness

Pathways

Methylation
Cell Differentiation
Cell Proliferation
Dna Methylation
Cell Cycle
Rna Interference
Gastrulation
Localization
Transport
Heterochromatin Organization
Neural Tube Closure
Cell Cycle Checkpoint
Dna Hypermethylation

Muscle Cell Differentiation
Dna Hypomethylation
Regulation Of Gene Expression
Transcytosis
Schwann Cell Proliferation
Translation
Histone Lysine Methylation

PTMs

Methylation

Demethylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ASCL2

References

PMID: 9175731 by Alders M., et al. The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts.

PMID: 11440538 by Westerman B.A., et al. The human Achaete Scute homolog 2 gene contains two promotors, generating overlapping transcripts and encoding two proteins with different nuclear localization.