ATAD3A Antibodies

AND ATAD3A ELISA kits, ATAD3A Proteins

Many biological assays use antibodies to detect ATAD3A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATAD3A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATAD3A antibodies...

We validate the specificity of these antibodies to ATAD3A by testing them on tissues known to express ATAD3A positively and negatively. Browse below to find the ATAD3A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATAD3A Infographic by Boster Bio

All ATAD3A Products

Product

Figures

Specificity

Applications

Price

Anti-ATAD3A Antibody

Human, Mouse, Rat

ELISA, IF, ICC, WB

$449
Cat # A06057
0.1 mg

Anti-ATAD3A Antibody

Human, Mouse

IHC, WB

$405
Cat # A06057-1
100ul

ATAD3A (NM_018188) Human Over-expression Lysate

Human

$960
Cat # LS055210
100 µg

ATAD3A Overview

Facts about ATPase family AAA domain-containing protein 3A.

ATAD3A 3D structure. Source: alphafold

ATPase family AAA domain-containing protein 3A (ATAD3A)

Critical for mitochondrial network organization, mitochondrial metabolism and cell growth in cellular and receptor level. May play a significant role in mitochondrial protein synthesis.

May also take part in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability.

Gene Information

Human
Gene Name:	ATAD3A
Uniprot:	Q9NVI7
Entrez:	55210

Family

Belongs to:

AAA ATPase family

Alternative Names

ATPase family AAA domain-containing protein 3A; ATPase family, AAA domain containing 3A; FLJ10709; FLJ35514

Molecular Weight

Mass (kDA):
71.369 kDA

Genomic Context


Human

Location:	1p36.33
Sequence:	1; NC_000001.11 (1512143..1534687)

Tissue Specificity

Overexpressed in lung adenocarcinomas (at protein level).

Subcellular Localizations

Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid. In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane (PubMed:20349121, PubMed:20154147). The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (PubMed:18063578).

Diseases

Aortic Aneurysm, Abdominal
Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Tumor Progression
Optic Atrophy
Uterine Cervical Neoplasm
Mitochondrial Diseases
Glioma
Endometrial Polyp
Human Papilloma Virus Infection
Neoplasm Invasiveness
Malignant Tumor Of Cervix

Leukemia, Myelocytic, Acute
Endometriosis, Site Unspecified
Posttransfusion Purpura
Myeloid Leukemia
Adenocarcinoma
Malignant Neoplasm Of Prostate
Lung Neoplasms

Pathways

Localization
Drug Resistance
Cell Growth
Transport
Nucleoid Organization
Gene Silencing
Proteolysis
Oxidative Phosphorylation
Regeneration
Translation
Mitochondrial Nucleoid Organization

Cholesterol Import
Pathogenesis
Rna Interference
Autophagy
Secretion

PTMs

Phosphorylation

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATAD3A

References

PMID: 20332122 by Fang H.Y., et al. ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells.

PMID: 17210950 by He J., et al. The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization.