Protein atonal homolog 1 Antibodies

AND ATOH1 ELISA kits, Protein atonal homolog 1 Proteins

Many biological assays use antibodies to detect Protein atonal homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein atonal homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein atonal homolog 1 antibodies...

We validate the specificity of these antibodies to Protein atonal homolog 1 by testing them on tissues known to express ATOH1 positively and negatively. Browse below to find the ATOH1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATOH1 Infographic by Boster Bio

All ATOH1 Products

Product

Figures

Specificity

Applications

Price

Anti-MATH1/HATH1/ATOH1 Antibody Picoband™

4 Q&As

Human, Rat

$370
Cat # A02207-1
100 μg/vial

Human ATOH1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ92858
Starting from 20ug

Anti-ATOH1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M02207
100 μl/vial

ATOH1 (NM_005172) Human Over-expression Lysate

Human

$628
Cat # LS000474
100 µg

ATOH1 Overview

Facts about Protein atonal homolog 1.

ATOH1 3D structure. Source: alphafold

Protein atonal homolog 1 (ATOH1)

Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the action is totally antagonized by the negative regulator of neurogenesis HES1.

Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity). .

Gene Information

Human
Gene Name:	ATOH1
Uniprot:	Q92858
Entrez:	474

Family

Belongs to:

No superfamily

Alternative Names

ATH1protein atonal homolog 1; atonal homolog 1 (Drosophila); BHLHA14; bHLHa14Math1; Class A basic helix-loop-helix protein 14; HATH1; Helix-loop-helix protein hATH-1; MATH-1

Molecular Weight

Mass (kDA):
38.16 kDA

Genomic Context


Human

Location:	4q22.2
Sequence:	4; NC_000004.12 (93828753..93830964)

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Nervousness
Malignant Neoplasms
Medulloblastoma
Cerebellar Neoplasms
Cell Transformation, Neoplastic
Sensorineural Hearing Loss (disorder)
Complete Hearing Loss
Carcinoma
Malignant Tumor Of Colon
Colonic Neoplasms
Adenocarcinoma
Brain Neoplasms

Hyperplasia
Metaplasia
Malignant Paraganglionic Neoplasm
Colorectal Cancer
Colorectal Neoplasms
Congenital Abnormality
Adenoma

Pathways

Cell Differentiation
Hair Cell Differentiation
Regeneration
Cell Cycle
Neurogenesis
Cell Proliferation
Cell Development
Notch Signaling Pathway
Ear Development
Transdifferentiation
Inner Ear Development
Cell Migration
Innervation

Cell Death
Pathogenesis
Cell Fate Determination
Mitosis
Cell Division
Eye Development
Proprioception

PTMs

Methylation
Phosphorylation

Demethylation
Cleavage

Sumoylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATOH1

References

PMID: 8872459 by Ben-Arie N., et al. Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis.