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- Table of Contents
Facts about Potassium-transporting ATPase alpha chain 2.
Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane.
Responsible for potassium absorption in a variety of tissues..
Human | |
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Gene Name: | ATP12A |
Uniprot: | P54707 |
Entrez: | 479 |
Belongs to: |
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cation transport ATPase (P-type) (TC 3.A.3) family |
Potassium-transporting ATPase alpha chain 2
Mass (kDA):
115.511 kDA
Human | |
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Location: | 13q12.12|13q12.1-q12.3 |
Sequence: | 13; NC_000013.11 (24680408..24712472) |
Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).
Membrane; Multi-pass membrane protein.
PMID: 8045293 by Grishin A.V., et al. Cloning and characterization of the entire cDNA encoded by ATP1AL1 -- a member of the human Na,K/H,K-ATPase gene family.
PMID: 8838794 by Sverdlov V.E., et al. Genomic organization of the human ATP1AL1 gene encoding a ouabain- sensitive H,K-ATPase.