ATP2A3 Antibodies

AND ATP2A3 ELISA kits, ATP2A3 Proteins

Many biological assays use antibodies to detect ATP2A3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATP2A3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATP2A3 antibodies...

We validate the specificity of these antibodies to ATP2A3 by testing them on tissues known to express ATP2A3 positively and negatively. Browse below to find the ATP2A3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATP2A3 Infographic by Boster Bio

All ATP2A3 Products

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Specificity

Applications

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Anti-SERCA3 ATPase/ATP2A3 Antibody Picoband®

5 Q&As

Anti-ATP2A3 antibody, RP1055, Western blottingAll lanes: Anti ATP2A3 (RP1055) at 0

Anti-ATP2A3 antibody, RP1055, IHC(P)IHC(P): Mouse Thymus Tissue

Anti-ATP2A3 antibody, RP1055,IHC(P) IHC(P): Rat Thymus Tissue

Human, Mouse, Rat

IHC, WB

$370
Cat # RP1055
100 μg/vial

SERCA3 (ATP2A3) (NM_174953) Human Recombinant Protein

Coomassie blue staining of purified ATP2A3 protein

$1062
Cat # PROTQ93084
20 µg

Anti-ATP2A3 Antibody (N-Term)

Human

IHC-P, WB

$299
Cat # M04597
50 µl

SERCA3 (ATP2A3) (NM_174953) Human Over-expression Lysate

Human

$960
Cat # LS000489
20 µg, 100 µg

ATP2A3 Overview

Facts about Sarcoplasmic/endoplasmic reticulum calcium ATPase 3.

ATP2A3 3D structure. Source: alphafold

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (ATP2A3)

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen.

Contributes to calcium sequestration involved in muscle excitation/contraction. .

Gene Information

Human
Gene Name:	ATP2A3
Uniprot:	Q93084
Entrez:	489

Family

Belongs to:

cation transport ATPase (P-type) (TC 3.A.3) family

Alternative Names

adenosine triphosphatase, calcium; ATPase, Ca(2+)-transporting, ubiquitous; ATPase, Ca++ transporting, ubiquitous; Calcium pump 3; EC 3.6.3; EC 3.6.3.8; sarco/endoplasmic reticulum Ca2+ ATPase; sarco/endoplasmic reticulum Ca2+ -ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA3calcium-translocating P-type ATPase; SR Ca(2+)-ATPase 3

Molecular Weight

Mass (kDA):
113.977 kDA

Genomic Context


Human

Location:	17p13.2
Sequence:	17; NC_000017.11 (3923869..3964464, complement)

Tissue Specificity

Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues. Expressed in cell lineages of hematopoietic, epithelial, or embryonic origin and also expressed in several cancer cell lines.

Subcellular Localizations

Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Endometriosis, Site Unspecified
Diabetes Mellitus
Malignant Tumor Of Colon
Carcinoma
Colonic Neoplasms
Malignant Squamous Cell Neoplasm
Neoplasms
Adenocarcinoma
Heart Failure
Diabetes Mellitus, Non-insulin-dependent
Diabetes Mellitus, Insulin-dependent
Dermatologic Disorders

Keratosis Follicularis
Head And Neck Carcinoma
Cell Transformation, Neoplastic
Hypertensive Disease
Stomach Neoplasms
Adenoma
Adolescent Idiopathic Scoliosis

Pathways

Secretion
Transport
Insulin Secretion
Localization
Cell Differentiation
Proteolysis
Translation
Methylation
Cell Death
Platelet Maturation
Cell Growth
Regulation Of Insulin Secretion
Pathogenesis

Cell Adhesion
Programmed Cell Death
Aging
Response To Biotin
Platelet Aggregation
Glucose Homeostasis
Store-operated Calcium Entry

PTMs

Phosphorylation

Methylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATP2A3

References

PMID: 8809064 by Dode L., et al. cDNA cloning, expression and chromosomal localization of the human sarco/endoplasmic reticulum Ca(2+)-ATPase 3 gene.

PMID: 9593748 by Dode L., et al. Structure of the human sarco/endoplasmic reticulum Ca2+-ATPase 3 gene. Promoter analysis and alternative splicing of the SERCA3 pre- mRNA.