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- Table of Contents
Facts about Plasma membrane calcium-transporting ATPase 1.
Human | |
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Gene Name: | ATP2B1 |
Uniprot: | P20020 |
Entrez: | 490 |
Belongs to: |
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cation transport ATPase (P-type) (TC 3.A.3) family |
ATPase, Ca++ transporting, plasma membrane 1; EC 3.6.3; EC 3.6.3.8; Plasma membrane calcium ATPase isoform 1; plasma membrane calcium ATPase; Plasma membrane calcium pump isoform 1; plasma membrane calcium pump; plasma membrane calcium-ATPase; PMCA1kb; PMCA1plasma membrane calcium-transporting ATPase 1
Mass (kDA):
134.685 kDA
Human | |
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Location: | 12q21.33 |
Sequence: | 12; NC_000012.12 (89588049..89709366, complement) |
Isoform B: Ubiquitously expressed. Isoform C: Found in brain cortex, skeletal muscle and heart muscle. Isoform D: Has only been found in fetal skeletal muscle. Isoform K: Found in small intestine and liver.
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane. Cell junction, synapse. Colocalizes with SV2A in photoreceptor synaptic terminals. Colocalizes with NPTN to the immunological synapse. Colocalizes with EPB41 to the basolateral membrane in enterocyte.
PMID: 2844759 by Verma A.K., et al. Complete primary structure of a human plasma membrane Ca2+ pump.
PMID: 8386431 by Kumar R., et al. Molecular cloning of a plasma membrane calcium pump from human osteoblasts.