ATP4A Antibodies

AND ATP4A ELISA kits, ATP4A Proteins

Many biological assays use antibodies to detect ATP4A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATP4A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATP4A antibodies...

We validate the specificity of these antibodies to ATP4A by testing them on tissues known to express ATP4A positively and negatively. Browse below to find the ATP4A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for ATP4A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ATP4A IHC Guide

ATP4A Infographic by Boster Bio

All ATP4A Products

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Product

Figures

Specificity

Applications

Price

Anti-ATP4A Antibody Picoband®

Western blot analysis of ATP4A using anti-ATP4A antibody (A08198-1)

IHC analysis of ATP4A using anti-ATP4A antibody (A08198-1)

Flow Cytometry analysis of Daudi cells using anti-ATP4A antibody (A08198-1)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # A08198-1
100 μg/vial

ATP4A (NM_000704) Human Over-expression Lysate

Human

$960
Cat # LS000495
20 µg, 100 µg

ATP4A Overview

Facts about Potassium-transporting ATPase alpha chain 1.

ATP4A 3D structure. Source: alphafold

Potassium-transporting ATPase alpha chain 1 (ATP4A)

Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane.
Responsible for acid production in the stomach.

Gene Information

Human
Gene Name:	ATP4A
Uniprot:	P20648
Entrez:	495

Family

Belongs to:

cation transport ATPase (P-type) (TC 3.A.3) family

Alternative Names

ATP6Agastric H; ATPase, H+/K+ exchanging, alpha polypeptide; ATPase, H+/K+ transporting, alpha polypeptide; EC 3.6.3; EC 3.6.3.10; gastric H; Gastric H(+)/K(+) ATPase subunit alpha; gastric H+/K+ ATPase alpha subunit; gastric hydrogen-potassium ATPase; H(+)-K(+)-ATPase alpha subunit; K-ATPase alpha subunit; K-ATPase catalytic subunit; potassium-transporting ATPase alpha chain 1; Proton pump

Molecular Weight

Mass (kDA):
114.119 kDA

Genomic Context


Human

Location:	19q13.12
Sequence:	19; NC_000019.10 (35550031..35563658, complement)

Tissue Specificity

Found in gastric mucosa.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Achlorhydria
Malignant Neoplasms
Gastritis, Atrophic
Anemia
Autoimmune Diseases
Gastritis
Autoimmune Reaction
Metaplasia
Anemia, Pernicious
Neoplasms
Tubal Metaplasia
Iron Deficiency Anemia

Malignant Neoplasm Of Stomach
Stomach Neoplasms
Neoplasm Metastasis
Helicobacter Infections
Polyps
Gastric Ulcer

Pathways

Acid Secretion
Secretion
Cell Proliferation
Gastric Acid Secretion
Cell Adhesion
Transport
Lactation
Ion Transport
Methylation
Fermentation
Cell Differentiation

Cell Growth
Angiogenesis
Mating
Pathogenesis
Regulation Of Blood Pressure

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATP4A

References

PMID: 2160952 by Maeda M., et al. Human gastric (H+ + K+)-ATPase gene. Similarity to (Na+ + K+)-ATPase genes in exon/intron organization but difference in control region.

PMID: 2176086 by Newman P.R., et al. Structure of the human gastric H,K-ATPase gene and comparison of the 5'-flanking sequences of the human and rat genes.